Margaret A. Maglione

Margaret A. Maglione
Adjunct Staff
Off Site Office


B.A. in economics, Columbia University; M.P.P. in public policy, University of Southern California


Margaret Maglione is an adjunct researcher at the RAND Corporation. From 2006 to 2015, she was the associate director of the Southern California Evidence-Based Practice Center (EPC), one of the leading institutions worldwide for the creation of systematic reviews, meta-analyses, and other evidence-based products. Maglione has led projects funded by the U.S. Agency for Healthcare Research and Quality, the Centers for Medicare & Medicaid Services, the Veterans Administration, the Health Resources and Services Administration, the National Institutes of Health, and various specialty societies and charitable foundations.

Maglione's work often addresses controversial topics, as reflected by her work on AIDS in the early days of the epidemic and her previous projects at UCLA's Drug Abuse Research Center. Her RAND research topics have been diverse, ranging from the safety and efficacy of dietary supplements containing ephedra to a 2011 systematic review on the effectiveness of interventions for autism spectrum disorders in children and work with a panel of experts to develop new guidelines. In 2013, Maglione led a project assessing the safety of vaccines recommended for routine use in children, adolescents, and adults.

Maglione received a B.A. in economics from Columbia University and an M.P.P. in public policy from the University of Southern California.

Recent Projects

  • Mindfulness Meditation for Chronic Pain
  • Mindfulness Meditation for Smoking Cessatoin
  • Safety of Vaccines Routinely Recommended in the U.S.
  • Effectiveness of Interventions for Children with Autism / Development of Guidelines
  • Safety & Efficacy of Atypical Antipsychotics for Off-label Uses

Selected Publications

Maglione M, Das L, Raaen L, Smith A, Chari R, Newberry S, Hempel S, Shanman R, Perry T, Goetz MB, Gidengil C., Safety of Vaccines Used for Routine Immunization in the United States, Agency for Healthcare Research and Quality, 2014

Maglione, MA, Das L, Raaen L, Smith A, Chari R, Newberry S, Shanman RM, Perry T, Goetz B, Gidengil CA, "Safety of Vaccines Used for Routine Immunization of US Children: A Systematic Review," Pediatrics, 134(2), 2014

Maglione, M, Maggard Gibbons, M, Livhits, M, Ewing, B, Hu, J, Ruelaz Maher, A, Li, Z, Shanman, R, Perry, T, Shekelle, P.G., Comparative Effectiveness of Bariatric Surgery and Nonsurgical Therapy in Adults With Metabolic Conditions and a Body Mass Index of 30.0 to 34.9 kg/m², Agency for Healthcare Research and Quality, 2012

Maglione M, Gans D, Das L, Timbie J, Kasari, C, "Non-medical Interventions for Children with ASD: recommended Guidelines and Further Research Needs," Pediatrics, 130:S169-178, 2012

Maher AR, Maglione M, Bagley S, Suttorp M, Hu JH, Ewing B, Wang Z, Timmer M, Sultzer D, Shekelle PG, "Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis," Journal of the American Medical Association, 306(12):1359-69, 2011

Maglione M, Ruelaz Maher A, Hu J, Wang Z, Shanman R, Shekelle PG, Roth B, Hilton L, Suttorp MJ, Ewing BA, Motala A, Perry T., Off-Label Use of Atypical Antipsychotics: An Update. Comparative Effectiveness Review No. 43., Agency for Healthcare Research and Quality (EP-201100-​275), 2011

Maglione, M, Larson, C., Gianotti, T, and Lapin, P., "Use of Medicare Summary Notice (MSN) inserts to generate interest in the Medicare Stop Smoking Program," American Journal of Health Promotion, 21(5), 2007

Maglione, M, Miotto, K, Iguchi, M., Jungvig, L, Morton, S, and Shekelle, P., "Psychiatric effects of ephedra use - an analysis of FDA adverse event reports," American Journal of Psychiatry, 162:189-191, 2005

Honors & Awards

  • Game Changer of the Year - Pediatrics, 2012, MedScape
  • Gold Medal Award, 2007, RAND Corporation