Margaret A. Maglione

Policy Analyst; Associate Director, Southern California Evidence-Based Practice Center
Santa Monica Office

Education

B.A. in economics, Columbia University; M.P.P. in public policy, University of Southern California

Overview

Biography

Margaret A. Maglione is the Associate Director of the Southern California Evidence-Based Practice Center (EPC) at the RAND Corporation. The EPC is one of the leading institutions worldwide for the development of systematic reviews and meta-analyses on the safety and efficacy of health and mental health treatments, prevention interventions, and medications. Since starting at the EPC in 1999, she has led projects funded by the U.S. Agency for Healthcare Research and Quality (AHRQ), the Center for Medicaid & Medicare Services (CMS), and various branches of the National Institutes Of Health (NIH). Her work often focuses on controversial issues such food allergy in children, effectiveness of interventions for children with autism, and bariatric surgery as treatment for diabetes. She is currently leading a project on the safety of vaccines recommended for routine use in children, adolescents, and adults.

Research Focus

Recent Projects

  • Effectiveness of Interventions for Children w Autism / Development of Guidelines
  • Safety & Efficacy of Atypical Antipsychotics for Off-label Uses
  • Incidence, Prevalence, Treatment, and Prevention of Food Allergies
  • Bariatric Surgery & Metabolic Conditions

Publications

Nonmedical Interventions for Children with ASD: Recommended Guidelines and Further Research Needs - 2012

Depression and Medication Adherence in the Treatment of Chronic Diseases in the United States: A Meta-Analysis - 2011

Development Quality Criteria to Evaluate Nontherapeutic Studies of Incidence, Prevalence, or Risk Factors of Chronic Diseases: Pilot Study of New Checklists - 2011

Efficacy and Comparative Effectiveness of Atypical Antipsychotic Medications for Off-Label Uses in Adults: A Systematic Review and Meta-Analysis - 2011

Empirical Evidence of Associations Between Trial Quality and Effect Size - 2011

Off-label Use of Atypical Antipsychotics: An Update - 2011

Preventing Obesity and Its Consequences: Highlights of RAND Health Research - 2011

Updating Comparative Effectiveness Reviews: Current Efforts in AHRQ's Effective Health Care Program - 2011

A Cost-Effectiveness Analysis of a Proposed National Falls Prevention Program - 2010

Diagnosing and Managing Common Food Allergies: A Systematic Review - 2010

Diagnosing and Treating Food Allergies: The State of the Research - 2010

Prevalence, Natural History, Diagnosis, and Treatment of Food Allergy: A Systematic Review of the Evidence - 2010

Costs and Benefits of Health Information Technology: New Trends from the Literature - 2009

Evidence for Improving Palliative Care at the End of Life: A Systematic Review - 2008

Pregnancy and Fertility Following Bariatric Surgery: A Systematic Review - 2008

Systematic Review: Comparative Effectiveness of Treatments to Prevent Fractures in Men and Women with Low Bone Density or Osteoporosis - 2008

The Effectiveness of Covering Smoking Cessation Services for Medicare Beneficiaries - 2008

A Systematic Review of Measures of End-of-Life Care and Its Outcomes - 2007

Antiretroviral (ARV) Drug Resistance in the Developing World - 2007

Efficacy and Comparative Effectiveness of Off-Label Use of Atypical Antipsychotics: Executive Summary - 2007

Use of Medicare Summary Notice Inserts to Generate Interest in the Medicare Stop Smoking Program - 2007

Drug Class Review on Antiepileptic Drugs in Bipolar Mood Disorder, Neuropathic Pain, and Fibromyalgia: Final Report - 2006

Is Conventional Wisdom Wrong? Coverage for Substance Abuse Treatment Under Medicaid Managed Care - 2006

Managing Medicaid Behavioral Health Care: Findings of a National Survey in the Year 2000 - 2006

Systematic Review: Impact of Health Information Technology on Quality, Efficiency, and Costs of Medical Care - 2006

Meta-analysis: Pharmacologic Treatment of Obesity - 2005

Meta-analysis: Surgical Treatment of Obesity - 2005

Meta-analysis: Chronic Disease Self-Management Programs for Older Adults - 2005

Methodological Approaches for a Systematic Review of End-of-Life Care - 2005

Psychiatric Effects of Ephedra Use: An Analysis of Food and Drug Administration Reports of Adverse Events - 2005

Psychiatric Symptoms Associated with Ephedra Use - 2005

RAND Review: Vol. 29, No. 3, Fall 2005 - 2005

Some Prescription Diet Drugs Promote Weight Loss - 2005

Weight Loss Surgery is More Effective Than Diet and Exercise in Helping Severely Obese People Lose Weight - 2005

End-of-life Care and Outcomes: Prepared By Southern California Evidence-based Practice Center RAND Corporation ; Principal Investigators, Karl Lorenz, Joanne Lynn - 2004

Interventions for the Prevention of Falls in Older Adults: Systematic Review and Meta-Analysis of Randomised Clinical Trials - 2004

Pharmacological and Surgical Treatment of Obesity - 2004

Smoking-cessation Interventions By Type of Provider: A Meta-Analysis - 2004

Chronic Disease Self Management for Diabetes, Osteoarthritis, Post-Myocardial Infarction Care, and Hypertension - 2003

Efficacy and Safety of Ephedra and Ephedrine for Weight Loss and Athletic Performance: A Meta-Analysis - 2003

Efficacy of Angiotensin-Converting Enzyme Inhibitors and Beta-Blockers in the Management of Left Ventricular Systolic Dysfunction According to Race, Gender and Diabetic Status: A Meta-Analysis of Major Clinical Trials - 2003

Ephedra: Is It Worth the Risk? - 2003

Ephedra: Is It Worth the Risk? - 2003

Ephedra and Ephedrine for Weight Loss and Athletic Performance Enhancement: Clinical Efficacy and Side Effects - 2003

Exercise Programs for Older Adults: A Systematic Review and Meta-analysis - 2003

Falls Prevention Interventions in the Medicare Population - 2003

Health Risk Appraisals and Medicare - 2003

Interventions that Increase the Utilization of Medicare-Funded Preventive Services for Persons Age 65 and Older - 2003

Interventions to Promote Smoking Cessation in the Medicare Population - 2003

Pharmacologic Management of Heart Failure and Left Ventricular Systolic Dysfunction: Effect in Female, Black, and Diabetic Patients, and Cost-Effectiveness - 2003

RAND Review: Vol. 27, No. 1, Spring 2003 - 2003

Interventions That Increase Use of Adult Immunization and Cancer Screening Services: A Meta-Analysis - 2002

Mass Mailings Have Little Effect on Utilization of Influenza Vaccine Among Medicare Beneficiaries - 2002

Correlates of Outpatient Drug Treatment Drop-Out Among Methamphetamine Users - 2000

Residential Treatment of Methamphetamine Users: Correlates of Drop-Out from California Alcohol and Drug Data System (CADDS), 1994-1997 - 2000

Matching Clients' Needs with Drug Treatment Services - 1999