Publications
Below is a list of current EPC publications. Publications listed are associated with current EPC projects. Projects marked with an * are currently in progress.
Clinical Care Publications
Aging, Healthy
Preventive Services for Persons 65 and Older
Rubenstein L, Shekelle P, Stone E, Maglione M, Hirt M, Mojica W, Srikanthan P, Tomizawa T, Morton S, Chao B, Roth E, Breuder T. Interventions that Increase the Utilization of Medicare-Funded Preventive Services for Persons Age 65 and Older. Evidence Report prepared for the US Department of Health and Human Services, Health Care Financing Administration, 7500 Security Blvd., Baltimore MD. 21244-1850, Contract No. 500-98-0281.
Journal Articles:
Stone EG, Morton SC, Hulscher ME, Maglione MA, Roth EA, Grimshaw JM, Mittman BS, Rubenstein LV, Rubenstein LZ, Shekelle PG. Interventions that increase use of adult immunization and cancer screening services: A meta-analysis of 218 controlled studies. Ann Intern Med. 2002 May 7; 136(9):641-51.
Maglione MA, Stone EG, Shekelle PG. Mass mailings have little effect on utilization of influenza vaccine among Medicare beneficiaries. Am J Prev Med. 2002 July; 23(1):43-46.Conference Presentations:
"Improving Flu Vaccinations in Older Adults," (Authors: Shekelle PG et al.) National Adult Immunization Conference, Dallas, Texas, June 21-22, 1999.
"Meta-analysis of Improving Flu Vaccinations in Older Adults," (Authors: Shekelle PG et al.) Community Preventive Services Task Force, Centers for Disease Control, Atlanta, Georgia, June 22, 1999.
Smoking Cessation
Rubenstein L, Shekelle P, Stone E, Maglione M, Boyle K, Hoffman V, Klein K, Mojica W, Vaughn G, Morton S, Roth E, Chao B, Wu S, Joyce G. Interventions to Promote Smoking Cessation in the Medicare Population. Evidence Report prepared for the US Department of Health and Human Services, Health Care Financing Administration, 7500 Security Blvd., Baltimore MD. 21244-1850, Contract No. 500-98-0281.
Journal Article:
Mojica WA, Suttorp MJ, Sherman SE, Morton SC, Roth EA, Maglione MA, Rhodes SL, Shekelle PG. Smoking Cessation Interventions by Type of Provider: A Meta-analysis, American Journal of Preventive Medicine, Vol. 26, No. 5, June 2004, pp. 391-401
Conference Presentation:
"A review of effectiveness of smoking cessation interventions: Implications for Medicare," (Authors: Shekelle PG, Morton SC, Maglione M, Mojica W), American Public Health Association 129th Annual Meeting, Atlanta, October 2001
Health Risk Appraisals and Medicare
Rubenstein L, Shekelle P, Tucker J, Maglione M, Morton S, Roth E, Chao B, Rhodes S, Wu S, Newberry S. Health Risk Appraisals and Medicare. Evidence Report prepared for the US Department of Health and Human Services, Health Care Financing Administration, 7500 Security Blvd., Baltimore MD. 21244-1850, Contract No. 500-98-0281.
Chiropractic
Journal Article:
Coulter ID. Competing Views of Chiropractic: Health Services Research Versus Ethnographic Observation. Healing by Hand: Manual Medicine and Bonesetting in Global Perspective, Chapter 3, IN: Oths KS, Hinojosa SZ (eds.), AltaMira Press.
Chronic Disease Self-Management
Shekelle P, Rubenstein L, Maglione M, Chodosh J, Mojica W, Morton S, Suttorp M, Roth E, Jungvig L, Wu S. Chronic Disease Self-Management for Diabetes, Osteoarthritis, Post-Myocardial Infarction Care, and Hypertension. Evidence Report prepared for the US Department of Health and Human Services, Health Care Financing Administration, 7500 Security Blvd., Baltimore MD. 21244-1850, Contract No. 500-98-0281.
Journal Article:
Chodosh J, Morton SC, Mojica W, Maglione M, Suttorp MJ, Hilton L, Rhodes S, Shekelle P, Southern California Evidence-Based Practice Center, RAND Health Division. Meta-Analysis: Chronic Disease Self-Management Programs for Older Adults, Annals of Internal Medicine, Vol. 143, No. 6, Sept 20 2005, pp. 427-438, W99-W106.
Falls Prevention
Shekelle P, Rubenstein L, Maglione M, Chang J, Mojica W, Morton S, Suttorp M, Roth E, Rhodes S, Wu S, Newberry S. Falls Prevention Interventions in the Medicare Population. Evidence Report prepared for the US Department of Health and Human Services, Health Care Financing Administration, 7500 Security Blvd., Baltimore MD. 21244-1850, Contract No. 500-98-0281.
Journal Article:
Chang JT, Morton SC, Rubinstein LZ, Mojica WA, Maglione M, Suttorp MJ, Roth EA, Shekelle PG. Interventions for the Prevention of Falls in Older Adults: Systematic Review and Meta-analysis of Randomized Clinical Trials, British Medical Journal, Vol.328, No. 7441, March 20 2004, pp. 680-687
Exercise Programs for Older Adults: A Systematic Review and Meta-analysis
Shekelle P, Maglione M, Mojica W, Morton S, Suttorp M, Tu W, Roth E, Jungvig L, Rhodes S, Wu S, Rubenstein L. Exercise Programs for Older Adults: A Systematic Review and Meta-analysis. Evidence Report prepared for the US Department of Health and Human Services, Centers for Medicare and Medicaid Services, 7500 Security Blvd., Baltimore MD. 21244-1850, Contract No. 500-98-0281.
Cancer and Blood Disorders
Antiretroviral Drug Resistance
Maglione M, Geotz M, Wang Z, Wagner G, Hilton L, Carter J, Tringale C, Newberry S, Shekelle P. Antiretroviral (ARV) Drug Resistance in the Developing World. Evidence Report/Technology Assessment No. 156. Rockeville, MD: Agency for Healthcare Research and Quality, No. 07-E014, Sept 2007
Cancer Care Quality Measures: Symptoms and End-of-Life Care
Lorenz K, Lynn K, Dy S, et al. Cancer Care Quality Measures: Symptoms and End-of-Life Care. Evidence Report/Technology Assessment No. 137. (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-02-003.) AHRQ Publication No. 06-E001. Rockville, MD: Agency for Healthcare Research and Quality. May 2006.
Complementary and Alternative Therapies for Cancer: A Best Case Series
Shekelle P, Coulter I, Hardy M, Morton SC, Favreau J, Gagne J, Coulter SA, Newberry S, Udani J, Roth E, Jungvig L. Best Case Series for the Use of Immuno-Augmentation Therapy and Naltrexone for the Treatment of Cancer. Evidence Report/Technology Assessment: Number 78. AHRQ Publication Number 03-E029, April 2003. Agency for Healthcare Research and Quality, Rockville, MD.
Executive Summary (PDF)
Omega-3 Fatty Acids and Cancer
Maclean CH, Newberry SJ, Mojica WA, Issa AM, Morton SC, Garland RH, Hilton LG, Traina SB, Shekelle PG. Effects of Omega-3 Fatty Acids on Cancer. Evidence Report/Technology Assessment No. 113 (Prepared by the Southern California Evidence-based Practice Center, under Contract No. 290-02-0003). AHRQ Publication No. 05-E010-2. Rockville MD. Agency for Healthcare Research and Quality. February 2005.
Full Report (PDF)
Journal Article:
MacLean CH, Newberry SJ. Omega-3 Fatty Acids and Cancer Risk-Reply. The Journal of the American Medical Association, Vol. 296, No. 3, [Letters], July 19 2006, p.282
Complementary and Alternative Medicine
(Technical Support for the National Center for Complementary and Alternative Medicine)
Ayurvedic Interventions for Diabetes Mellitus
Hardy M, Coulter I, Venuturupalli S, Roth EA, Favreau J, Morton SC, Shekelle P. Ayurvedic Interventions for Diabetes Mellitus: A Systematic Review Evidence Report/Technology Assessment No. 41, Agency for Healthcare Research and Quality, Rockville, MD, Publication No.01-E040, September 2001
Journal Article:
Shekelle P, Hardy M, Morton SC, Coulter I, Venuturupalli S, Favreau J, Hilton LK. Are Ayurvedic Herbs for Diabetes Mellitus Effective? The Journal of Family Practice, Vol. 54, No. 10, Oct 2005, pp. 876-886
Chiropractic
Journal Article:
Coulter ID. Competing Views of Chiropractic: Health Services Research Versus Ethnographic Observation. Healing by Hand: Manual Medicine and Bonesetting in Global Perspective, Chapter 3, IN: Oths KS, Hinojosa SZ (eds.), AltaMira Press.
Hospital-based Center for Integrative Medicine
Journal Article:
Coulter ID, Ellison MA, Hilton L, Rhodes H, Ryan G. So. California Evidence-Based Practice Center. Hospital-Based Integrative Medicine: A Case Study of the Barriers and Factors Facilitating the Creation of a Center, MG-591-NCCAM, 2007.
Mind-Body Interventions for Gastrointestinal Conditions
Coulter ID, Hardy ML, Favreau JT, Elfenbaum PD, Morton SC, Roth EA, Genovese BJ, Shekelle PG. Mind-Body Interventions for Gastrointestinal Conditions Evidence Report/Technology Assessment Report No. 40, Agency For Healthcare Research And Quality, Rockville, MD, Publication No.01-E030, July 2001
Journal Article:
Coulter ID, Favreau JT, Hardy ML, Morton SC, Roth EA, Shekelle PG. Biofeedback Interventions for Gastrointestinal Conditions: A systematic review. Altern Ther Health Med. 2002 May-Jun;8(3):76-83
S-Adenosyl Methionine (SAM-E) for Treatment of Depression, Osteoarthritis, and Liver Disease
Hardy M, Coulter I, Favreau J, Morton SC, Venuturupalli S, Chiapelli F, Rossi, Orshansky G, Jungvig L, Roth E, Suttorp M, Newberry S, Shekelle P, S-Adenosyl-L-Methionine for Treatment of Depression, Osteoarthritis, and Liver Disease. Summary, Evidence Report/Technology Assessment: Number 64. AHRQ Publication No. 02-E033, August 2002. Agency for Healthcare Research and Quality, Rockville, MD.
Complementary and Alternative Therapies for Cancer: A Best Case Series
Shekelle P, Coulter I, Hardy M, Morton SC, Favreau J, Gagne J, Coulter SA, Newberry S, Udani J, Roth E, Jungvig L. Best Case Series for the Use of Immuno-Augmentation Therapy and Naltrexone for the Treatment of Cancer. Evidence Report/Technology Assessment: Number 78. AHRQ Publication Number 03-E029, April 2003. Agency for Healthcare Research and Quality, Rockville, MD.
Antioxidants for Cancer
Shekelle P, Morton S, Hardy M. Effect of the Supplemental Use of Antioxidants Vitamin C, Vitamin E, and the Coenzyme Q10 for the Prevention and Treatment of Cancer. Evidence Report/Technology Assessment No. 75 (Prepared by Southern California-RAND Evidence-based Practice Center, under Contract No 290-97-0001). AHRQ Publication No. 03-E043. Rockville, MD: Agency for Healthcare Research and Quality. July 2003.
Journal Article:
Coulter ID, Hardy ML, Morton SC, Hilton LG, Tu W, Valentine D, Shekelle PG. Antioxidants Vitamin C and Vitamin E for the Prevention and Treatment of Cancer, Journal of General Internal Medicine, Vol. 21, No. 7, July 2006, pp. 735-744
Antioxidants for Cardiovascular Disease
Shekelle P, Morton S, Hardy M. Effect of Supplemental Antioxidants Vitamin C, Vitamin E, and Coenzyme Q10 for the Prevention and Treatment of Cardiovascular Disease. Evidence Report/Technology Assessment No. 83 (Prepared by Southern California-RAND Evidence-based Practice Center, under Contract No 290-97-0001). AHRQ Publication No. 03-E043. Rockville, MD: Agency for Healthcare Research and Quality. July 2003.
Journal Article:
Shekelle PG, Morton SC, Jungvig LK, Udani J, Spar M, Tu W, Suttorp MJ, Coulter I, Newberry SJ, Hardy M. Effect of Supplemental Vitamin E for the Prevention and Treatment of Cardiovascular Disease, Journal of General Internal Medicine, Vol. 19, No. 4, Apr 2004, pp. 380-389
Dietary Supplements
Antioxidants for Cancer (see above)
Antioxidants for Cardiovascular Disease (see above)
Ephedra: Clinical Efficacy and Side-effects
Shekelle PG, Hardy ML, Morton SC, Maglione M, Mojica WA, Suttorp MJ, Rhodes SL, Jungvig L, Gagne J. Ephedra and Ephedrine for Weight Loss and Athletic Performance Enhancement: Clinical Efficacy and Side Effects. Evidence Report/Technology Assessment No. 76 (Prepared by the SCEPC, RAND, AHRQ Pub. No. 03-E022, Rockville MD, February 2003.
Journal Articles:
Maglione M, Miotto K, Iguchi M, Hilton L, Shekelle P. Psychiatric Symptoms Associated with Ephedra Use, Expert Opinion on Drug Safety, Vol. 4, No. 5, Sept 2005, pp. 879-884.
Maglione M, Miotto K, Iguchi M, Jungvig L, Morton SC, Shekelle PG. Psychiatric Effects of Ephedra Use: An Analysis of Food and Drug Administration Reports of Adverse Events. American Journal of Psychiatry, Vol. 162, No. 1, Jan 2005, pp. 189-191.
Morton SC. Statistical Collaboration to Impact Policy Decisions. Statistics in Medicine, Vol. 24, No. 4, Jan 28 2005, pp. 493-501
Shekelle PG, Hardy ML, Morton SC, Maglione M, Mojica WA, Suttorp MJ, Rhodes SL, Jungvig L, Gagne J. Efficacy and Safety of Ephedra and Ephedrine for Weight Loss and Athletic Performance: A Meta-analysis, Journal of the American Medical Association, Vol. 289, No. 12, March 26, 2003, pp. 1537-1545.
Testimony:
Shekelle PG, Morton SC, Maglione M, Hardy ML, Suttorp MJ, Roth E, Jungvig L, Mojica WA, Cagne J, Rhodes SL, McKinnon E, Newberry S. Ephedra - Is It Worth the Risk? (Testimony submitted for the record to the NY State Senate Committee on Consumer Protection, 30 May 2003) CT-209, 2003.
Health Benefits of Omega-3 Fatty Acids
Omega-3 Fatty Acids and Cancer
MacLean CH, Newberry SJ, Mojica WA, Issa A, Khanna P, Lim YW, Morton SC, Suttorp M, Tu W, Hilton LG, Garland RH, Traina SB, Shekelle PG. Effects of Omega-3 Fatty Acids on Cancer, Evidence Report/Technology Assessment No. 113, Rockville, MD: Agency for Healthcare Research and Quality, Feb 2005.
Journal Article:
MacLean CH, Newberry SJ, Mojica WA, Khanna P, Issa AM, Suttorp MJ; Lim Y-W, Traina SB, Hilton L, Garland R, Morton SC. Effects of Omega-3 Fatty Acids on Cancer Risk, Journal of the American Medical Association, Vol. 294, No. 4, January 25, 2006, pp. 403-415.
Omega-3 Fatty Acids and Type II Diabetes, Immune Disorders, and Renal Disease
MacLean CH, Mojica, WA, Morton SC, Pencharz J, Hasenfeld Garland R, Tu W, Newberry SJ, Jungvig LK, Grossman J, Khanna P, Rhodes S, Shekelle P. Effects of Omega-3 Fatty Acids on Lipids and Glycemic Control in Type II Diabetes and the Metabolic Syndrome and on Inflammatory Bowel Disease, Rheumatoid Arthritis, Renal Disease, Systemic Lupus Erythematosus, and Osteoporosis. Evidence Report/Technology Assessment. No. 89 (Prepared by Southern California/RAND Evidence-based Practice Center, under Contract No. 290-02-0003). AHRQ Publication No. 04-E012-2. Rockville, MD: Agency for Healthcare Research and Quality. March 2004.
Journal Article:
MacLean CH, Mojica WA, Newberry SJ, Pencharz J, Garland RH, Tu W, Hilton LG, Gralnek IM, Rhodes S, Khanna P, Morton SC, Southern California Evidence-Based Practice Center. Systematic Review of the Effects of N-3 Fatty Acids in Inflammatory Bowel Disease, American Journal of Clinical Nutrition, Vol. 82, No. 3, Sept 2005, pp. 611-619.
Omega-3 Fatty Acids and Cognitive Functions and Neurological Disorders
MacLean CH, Issa AM, Newberry SJ, Mojica WA, Morton SC, Garland RH, Hilton LG, Traina SB, Shekelle PG. Effects of Omega-3 Fatty Acids on Cognitive Function with Aging, Dementia, and Neurological Diseases, Evidence Report/Technology Assessment No. 114, Rockville, MD: Agency for Healthcare Research and Quality, Feb 2005.
Conference Presentation:
Lessons Learned: Evaluating the Effects of Omega-3 Fatty Acids on Immune Disorders, Cancer, and Neurological Diseases (Newberry et al.), at an NIH ODS-sponsored workshop on Assessing the Health Effects of Bioactive Food Components, San Diego CA, April 1, 2005.
S-Adenosyl Methionine (SAM-E) for Treatment of Depression, Osteoarthritis, and Liver Disease (see above)
Ear, Nose, and Throat Conditions
Management of Acute Otitis Media in Children
Marcy M, Takata G, Chan L, Shekelle P, Mason W, Wachsman L, Ernst R, Hay J, Corley P, Morphew T, Ramicone E, Nicholson C. Management of Acute Otitis Media. Evidence Report/Technology Assessment No. 15 (Prepared by the Southern California Evidence-based Practice Center, under Contract No. 290-97-0001). AHRQ Publication Number 01-E010. Rockville MD. Agency for Healthcare Research and Quality. May 2001.
Journal Articles:
Takata GS, Chan LS, Shekelle P, et al. Evidence assessment of management of acute otitis media: I. the role of antibiotics in treatment of uncomplicated acute otitis media. Pediatrics. 2001 Aug;108(2):239-47.
Chan LS, Takata GS, Shekelle P, et al. Evidence assessment of management of acute otitis media: II. research gaps and priorities for future research. Pediatrics. 2001 Aug;108(2):248-54Other Publications:
Takata GS. "AHCPR Evidence Report on Acute Otitis Media". In Recent Advances in Otitis Media: Proceedings of the Seventh International Symposium. Lim DJ, Bluestone CD, Editors. B.C. Decker, Hamilton, Ontario. 2001.
Conference Presentations:
AHCPR Evidence Report on Acute Otitis Media (Author: Takata GS) 7th International Symposium on Recent Advances in Otitis Media, June 3, 1999
Diagnosis, Natural History, and Late Effects of Otitis Media with Effusion
Takata GS, Chan L, Morphew T, Morton S, Shekelle PG. Diagnosis, Natural History, and Late Effects of Otitis Media with Effusion. Evidence Report/Technology Assessment No. 55 (Prepared by the Southern California Evidence-based Practice Center, under Contract No. 290-97-0001). AHRQ Publication Number 02-E026. Rockville MD. Agency for Healthcare Research and Quality. June 2002.
Journal Article:
Takata GS, Chan LS, Morphew T, Mangione-Smith R, Morton SC, Shekelle P. Evidence Assessment of the Accuracy of Methods of Diagnosing Middle Ear Effusion in Children with Otitis Media with Effusion. Pediatrics, Vol. 112, No. 6, December 2003, pp. 1379-1387
Heart and Vascular Diseases
Diagnosis and Treatment of Heart Failure
Shekelle, Rich, Morton, Pharmacologic Management of Heart Failure and Left Ventricular Systolic Dysfunction: Effect in Female, Black, and Diabetic Patients and Cost-Effectiveness. Evidence Report/Technology Assessment No. 82 (Prepared by the Southern California Evidence-based Practice Center, under Contract No. 290-97-0001). AHRQ Publication Number 03-E045. Rockville MD. Agency for Healthcare Research and Quality. July 2003.
Journal Article:
Shekelle PG, Rich MW, Morton SC, Atkinson CS, Tu W, Maglione M, Rhodes S, Barrett M, Fonarow GC, Greenberg B, Heidenreich PA, Knabel T, Konstam MA, Steimle A, Warner Stevenson L. Efficacy of Angiotensin-Converting Enzyme Inhibitors and Beta-Blockers in the Management of Left Ventricular Systolic Dysfunction According to Race, Gender, and Diabetic Status. A Meta-Analysis of Major Clinical Trials. Journal of the American College of Cardiology, Vol. 41, No. 9, May 7 2003, pp. 1529-1538
Angiotensin II Receptor Antagonists
See: Related RAND ProjectFurmaga E, Glassman P, Rhodes S, Suttorp M, Mojica W, Morton S, Shekelle P. Drug Class Review on Angiotensin II Receptor Antagonists, Prepared by the Southern California Evidence-based Practice Center under contract to the Oregon Health and Science University for the Agency for Healthcare Research and Quality. February 2006.
Furmaga E, Glassman P, Rhodes S, Morton S, Shekelle P. Drug Class Review on Angiotensin II Receptor Antagonists, Prepared by the Southern California Evidence-based Practice Center under contract to the Oregon Health and Science University for the Agency for Healthcare Research and Quality. September 2004
Newer Antiplatelet Agents
See: Related RAND ProjectDailey JH, Glassman P, McDonagh M, Peterson K, Suttorp M, Chen S, Shekelle P. Drug Class Review on Newer Antiplatelet Agents. Prepared by the Southern California Evidence-based Practice Center under contract to the Oregon Health and Science University for the Agency for Healthcare Research and Quality. April 2007.
Prevention of Venous Thromboembolism
Velmahos G, Kern J, Chan L, Oder D, Murray J, Shekelle P. Prevention of Venous Thromboembolism After Injury. Evidence Report/Technology Assessment No. 22 (Prepared by the Southern California Evidence-based Practice Center, under Contract No. 290-97-0001). AHRQ Publication Number 01-E004. Rockville MD. Agency for Healthcare Research and Quality. Nov. 2000.
Journal Articles:
Velmahos GC, Kern J, Chan LS, Oder, D, Murray JA, Shekelle PG. Prevention of venous thromboembolism after injury: An evidence-based report. Part I: Analysis of risk factors and evaluation of the role of vena caval filters. J Trauma. 2000. 49:132-139.
Velmahos GC, Kern J, Chan LS, Oder, D, Murray JA, Shekelle PG. Prevention of venous thromboembolism after injury: An evidence-based report. Part II: Analysis of risk factors and evaluation of the role of vena caval filters. J Trauma. 2000. 49:140-144.
Velmahos GC, Oh Y, McCombs J, Oder D. An evidence-based cost-effectiveness model on methods of prevention of posttraumatic venous thromboembolism. J Trauma 2000 Dec;49(6):1059-64
Infectious Diseases
Antiretroviral Drug Resistance
Maglione M, Geotz M, Wang Z, Wagner G, Hilton L, Carter J, Tringale C, Newberry S, Shekelle P. Antiretroviral (ARV) Drug Resistance in the Developing World. Evidence Report/Technology Assessment No. 156. Rockeville, MD: Agency for Healthcare Research and Quality, No. 07-E014, Sept 2007
Kidney Conditions
Nutrition in Renal Disease
Shekelle P, Stone E, Kania S, Weingarten S, Snape M, Hirt M, Tomizawa T, Dorn G, Simone L. Nutrition in Chronic Renal Failure. Prepared by the Southern California Evidence-based Practice Center for the Kidney Foundation. May 2000.
Journal Article:
Clinical practice guidelines for nutrition in chronic renal failure. K/DOQI, National Kidney Foundation. Am J Kidney Dis 2000 Jun;35(6 Suppl 2):S1-140 Erratum in: Am J Kidney Dis 2001 Oct;38(4):917
Practice Guideline:
Mental Health
Drug Class Review on Antiepileptic Drugs in Bipolar Mood Disorder, Neuropathic Pain, and Fibromyalgia
Goodman F, Glassman P, Maglione M, Suttorp M, Rhodes S, Ma Q, Rolon C, Shekelle P. Final Report, Portland OR: Oregon Health and Science University for the AHRQ, May 2006.
Antiepileptic Drugs in Bipolar Mood Disorder, Neuropathic Pain, and Fibromyalgia
See: Related RAND ProjectGoodman F, Glassman P, Maglione M, Suttorp M, Rhodes S, Ma Q, Rolon C, Shekelle P. Drug Class Review on Antiepileptic Drugs in Bipolar Mood Disorder, Neuropathic Pain, and Fibromyalgia , Prepared by the Southern California Evidence-based Practice Center under contract to the Oregon Health and Science University for the Agency for Healthcare Research and Quality. May 2006.
Efficacy and Comparative Effectiveness of Off-label Uses of Atypical Antipsychotics
See: Related RAND ProjectShekelle P, Maglione M, Bagley S, Suttorp M, Mojica WA, Carter J, Rolon C, Hilton L, Zhou A, Chen S, Glassman P. Comparative Effectiveness of Off-Label Use of Atypical Antipsychotics. Comparative Effectiveness Review No. 6. (Prepared by the Southern California/RAND Evidence-based Practice Center under Contract No. 290-02-0003.) Rockville, MD: Agency for Healthcare Research and Quality. January 2007.
Metabolic, Nutritional, and Endocrine Conditions
Comparison of Therapies for Low Bone Density
MacLean C, Alexander A, Carter J, Chen S, Desai SB, Grossman J, Maglione M, McMahon M, McNamara M, Mojica W, Newberry S, Ranganath V, Suttorp M, Timmer M, Tringale C, Valentine D, Zhou A. Comparative Effectiveness of Treatments to Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis Comparative Effectiveness Review No. 12. Rockeville, MD: Agency for Healthcare Research and Quality, No. 08-EHC008-FF, Dec 2007
Obesity: Surgical and Pharmacological Treatments
Li Z, Maglione M, Tu W, Mojica W, Arterburn D, Shugarman LR, Hilton L, Suttorp M, Solomon V, Shekelle PG, Morton SC. Some Prescription Diet Drugs Promote Weight Loss, RAND, RB-9139, Aug 2005.
Maggard MA, Shugarman LR, Suttorp M, Maglione M, Sugarman HJ,Livingston EH, Nguyen NT, Li Z, Mojica WA, Hilton L, Rhodes S, Morton SC, Shekelle PG. Weight Loss Surgery is More Effective than Diet and Exercise in Helping Severely Obese People Lose Weight, RAND, RB-9140, Aug 2005.
Shekelle PG, Morton SC, Maglione MA, Suttorp M, Tu W, Li Z, Maggard M, Mojica WA, Shugarman L, Solomon V, Jungvig L, Newberry SJ, Mead D, Rhodes S. Pharmacological and Surgical Treatment of Obesity. Evidence Report/Technology Assessment No. 103. (Prepared by the Southern California-RAND Evidence-Based Practice Center, Santa Monica, CA, under contract Number 290-02-0003.) AHRQ Publication No. 04-E028-2. Rockville, MD: Agency for Healthcare Research and Quality. July 2004
Journal Articles:
Li Z, Maglione M, Tu W, Mojica W, Arterburn D, Shugarman L, Hilton L, Suttorp M, Shekelle P, Morton S. Meta-analysis: Pharmacologic Treatment of Obesity. Annals of Internal Medicine, Vol. 142 No. 7, April 2005, pp. 532-546, W88-W93.
Maggard MA, Shugarman LR, Suttorp M, Maglione M, Sugarman HJ, Livingston EH, Nguyen NT, Li Z, Mojica WA, Hilton L, Rhodes S, Morton SC, Shekelle PG. Meta-Analysis: Surgical Treatment of Obesity, Annals of Internal Medicine, Vol. 142, No. 7, April 2005, pp. 547-559, W94-W118.
Musculoskeletal Disorders
Meta-analysis of Disease Modifying Anti-rheumatic Drugs and Joint Erosions
MacLean C, Shekelle P. A Systematic Review of the Effects of Disease Modifying Anti-rheumatic Drugs on Radiographic Progression in Rheumatoid Arthritis. (Prepared by the Southern California Evidence-based Practice Center for Connectics Corporation, Spring 2002).
Nerve and Brain Conditions
Prevention and Management of Urinary Tract Infections in Paralyzed Persons
Vickrey B, Shekelle P, Morton S, Clark K, Pathak M, Kamberg C. Prevention and Management of Urinary Tract Infections in Paralyzed Persons. Evidence Report/Technology Assessment No. 6 (Prepared by the Southern California Evidence-based Practice Center, under Contract No. 290-97-0001). AHRQ Publication Number 99-E008. Rockville MD. Agency for Healthcare Research and Quality. February 1999.
Journal Articles:
Shekelle PG, Morton SC, Clark KA, et al. Systematic review of risk factors for urinary tract infection in adults with spinal cord dysfunction. The Journal of Spinal Cord Medicine, 1999;22(4):258-272.
Morton SC, Shekelle PG, Adams JL, et al. Antimicrobial prophylaxis for urinary tract infection in persons with spinal cord dysfunction. Arch Phys Med Rehabil. 2002 Jan;83(1):129-138.
Antiepileptic Drugs in Bipolar Mood Disorder, Neuropathic Pain, and Fibromyalgia
See: Related RAND ProjectGoodman F, Glassman P, Maglione M, Suttorp M, Rhodes S, Ma Q, Rolon C, Shekelle P. Drug Class Review on Antiepileptic Drugs in Bipolar Mood Disorder, Neuropathic Pain, and Fibromyalgia , Prepared by the Southern California Evidence-based Practice Center under contract to the Oregon Health and Science University for the Agency for Healthcare Research and Quality. May 2006.
Obstetric and Gynecological Disorders
Women Veterans' Health Research
Goldzweig CL, Balekian TM, Rolon C, Yano CM, Shekelle PG. The state of women veterans' health research. Results of a systematic literature review. J. Gen. Intern. Med. 2006 Mar;21 Suppl 3:S82-92.
Oral and Gastrointestinal Disorders
Systematic Review of the Relationship Between Nonsteroidal Anti-inflammatory Medications and Gastrointestinal Complications
MacLean C, Ofman J, Morton S, Straus W, Shekelle P. The Risk of Gastrointestinal Complications from Nonsteroidal Antiinflammatory Drugs: A Meta-analysis. Report prepared for Merck and Co., Inc. Contract No. Merck 9-4-97.
Journal Articles:
Ofman JJ, MacLean CH, Straus WL, et al. A meta-analysis of severe upper gastrointestinal complications of nonsteroidal anti-inflammatory drugs. J Rheumatol. 2002; 29(4):804-12.
Straus WL, Ofman JJ, MacLean C, Morton S, Berger ML, Roth EA, Shekelle P. Do NSAIDS cause dyspepsia? A meta-analysis evaluating alternative dyspepsia definitions. Am J Gastroenterol.2002; 97(8):1951-8.
Conference Presentations:
"Different Sampling Strategies for Identifying Eligible Studies: The Effect on Outcome of a Meta-analysis of NSAID-associated Dyspepsia," (Authors: Morton SC, MacLean CH, Ofman J, Roth E, Adams JL, Shekelle PG), The VII Cochrane Colloquium, Rome, Italy, October 1999.
"Unpublished Data from the US FDA New Drug Reviews: How Do They Compare to Published Data When Assessing NSAID Associated Dyspepsia?," (Authors: MacLean CH, Morton SC, Strauss WL, et al.), The VII Cochrane Colloquium, Rome, Italy, October 1999.
"Estimating the Risk of Gastrointestinal Perforations, Ulcers and Bleeds (PUBs) in Populations not Exposed to NSAIDs," (Authors: Strauss W, Ofman J, MacLean C, et al), The International Society for Pharmacoepidemiology, Boston, MA, August 1999.
"The Risk of Gastrointestinal Complications from NSAIDs: A Meta-analysis," (Authors: MacLean CH, Ofman J, Morton SC, et al), The Dept. of Veterans Affairs, 17th Annual HSRD Service Meeting, May 1999.
"The Risk of Dyspepsia and Serious GI Complications from NSAIDs: A Meta-analysis," (Authors: Ofman J, MacLean C, Morton SC, et al.), Gastroenterology, Vol. 116(4), part. 2, p. A270; Amer. Gastroenterological Assoc. Meetings, Orlando, FL, May 1999.
"Do NSAIDs Cause Dyspepsia? A Meta-Analysis Evaluating Alternative Definitions," (Authors: Strauss W, Ofman J, MacLean C, et al), Gastroenterology, Vol. 116(4), part. 2, p. A97; The American Gastroenterological Association Meetings, Orlando, FL, May 1999.
"The Risk of GI Complications from NSAIDs: A Meta-analysis," (Authors: Strauss W, MacLean C, Ofman J, et al.), Soc. for General Internal Medicine Meetings, San Francisco, CA, April 1999.
Pediatric Conditions
Management of Acute Otitis Media in Children (see above)
Diagnosis, Natural History, and Late Effects of Otitis Media with Effusion (see above)
Health Care Services Publications
Financing and Economic Incentives
Utilization of Medicare Physician Services
Beeuwkes-Buntin M, Laugesen M, Goldman D, et al. Determinants of Increases in Medicare Expenditure for Physicians' Services. (Prepared by Southern California Evidence-Based Practice Center/RAND under Contract No 290-97-0001.) AHRQ Publication. Rockville, MD: Agency for Healthcare Research and Quality. October 2003.
Journal Article:
Buntin MJB, Escarce JJ, Goldman D, Kan H, Laugesen MJ, Shekelle P. Increased Medicare Expenditures for Physicians' Services: What Are the Causes? Inquiry, Vol. 41, No. 1, Spring 2004, pp. 83-94
Information Technology
Electronic Health Information Technology Systems
Shekelle PG, Morton SC, Keeler EB. Costs and Benefits of Health Information Technology, Evidence Report/Technology Assessment No. 132. (Prepared by Southern California Evidence-Based Practice Center/RAND under Contract No 290-97-0001.) AHRQ Publication. Rockville, MD: Agency for Healthcare Research and Quality, April 2006.
Related Database at ahrq.gov
Journal Articles:
Shekelle P. Health Information Technology, Journal of the American Medical Association, In press.
Chaudhry B, Wang J, Wu S, Maglione M, Mojica W, Roth E, Morton SC, Shekelle PG. Systematic Review: Impact of Health Information Technology on Quality, Efficiency, and Costs of Medical Care, Annals of Internal Medicine, Vol. 144, No. 10, May 16 2006, pp. E12-E22, W1-W18.
Quality Improvement and Patient Safety
Cancer Care Quality Measures: Symptoms and End-of-Life Care
Lorenz K, Lynn K, Dy S, et al. Cancer Care Quality Measures: Symptoms and End-of-Life Care. Evidence Report/Technology Assessment No. 137. (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-02-003.) AHRQ Publication No. 06-E001. Rockville, MD: Agency for Healthcare Research and Quality. May 2006.
End-of-Life Care and Outcomes
Lorenz K, Lynn J, Morton S, Dy S, Mularski R, Shugarman L, Sun V, Wilkinson A, Maglione M, Shekelle P. End-of-Life Care and Outcomes. Evidence Report/Technology Assessment No. 110 (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-02-0003.) AHRQ Publication No.05-E004-2. Rockville, MD: Agency for Healthcare Research and Quality. October 2004.
Journal Article:
Dy SM, Shugarman LR, Lorenz KA, Mularski RA, and Lynn J, for the RAND Southern California Evidence-Based Practice Center. A Systematic Review of Satisfaction with Care at the End of Life, Journal of the American Geriatric Society (JAGS), January 2008; Vol. 56, No. 1, pp. 124–129.
Kutner, JS. Editorial - Assuring Quality End-of-Life Care: Imperative to Expand the Evidence Base in Concert with Growth of the Field, Jean S. Kutner, MD, MSPH; Journal of the American Geriatric Society (JAGS), January 2008; Vol. 56, No. 1, pp. 160-162.
Shugarman LR, Lorenz K, Lynn J. End-of-Life Care: An Agenda for Policy Improvement, Clinics in Geriatric Medicine, Vol. 21, No. 1, Feb 2005, pp. 255-272.
Healthy Aging (see above)
- Preventive Services for Persons 65 and Older
- Smoking Cessation
- Health Risk Appraisals and Medicare
- Chronic Disease Self Management
- Falls Prevention
- Exercise and Older Adults
Preventing Violence in Adolescents
Chan LS, Kipke MD, Schneir A, Iverson E, Warf C, Limbos MA, Shekelle P. Preventing Violence and Related Health-Risking Social Behaviors In Adolescents. Evidence Report/Technology Assessment No. 107 (Prepared by the Southern California Evidence-based Practice Center under Contract No. 290-02-2003.) AHRQ Publication No. 04-E032-2. Rockville, MD: Agency for Healthcare Research and Quality. December 2004.
Technical Publications
Methodology
Validity of AHRQ Clinical Practice Guidelines
Ortiz O, Eccles, M, Grimshaw J, et al. Current validity of clinical practice guidelines. Technical Review 6 (Contract No. 290-97-0001 to the Southern California Evidence-based Practice Center at RAND). AHRQ Publication No. 02-0035. Rockville (MD): Agency for Healthcare Research and Quality. September 2002
Journal Articles:
Shekelle PG, Eccles MP, Grimshaw JM, Woolf SH. When should clinical guidelines be updated? BMJ. 2001 Jul 21;323(7305):155-7.
Shekelle PG, Ortiz E, Rhodes S, Morton SC, Eccles MP, Grimshaw JM, Woolf SH. Validity of the Agency for Healthcare Research and Quality clinical practice guidelines: how quickly do guidelines become outdated? JAMA. 2001 Sep 26;286(12):1461-7.
Hasenfeld R, Shekelle PG. Is the Methodological Quality of Guidelines Declining in the US? Comparison of the Quality of US Agency for Health Care Policy and Research (AHCPR) Guidelines with Those Published Subsequently. Quality and Safety in Health Care, Vol. 12, No. 6, Dec 2003, pp. 428-434
Meta-regression Approaches: What, Why, When, and How?
Morton SC, Adams JL, Suttorp MG, Shekelle PG. Meta-Regression Approaches: What, Why, When, and How? Technical Review 8 (Prepared by Southern California-RAND Evidence-based Practice Center, under Contract No 290-97-0001), AHRQ Publication No. 04-0033, Rockville, MD: Agency for Healthcare Research and Quality, March 2004
Journal Articles:
Lorenz KA, Ryan GW, Morton SC, Chan KS, Wang S, Shekelle PG. A Qualitative Examination of Primary Care Providers' and Physician Managers' Uses and Views of Research Evidence, International Journal for Quality in Health Care, [Epub May 27 2005], Vol. 17, No. 5, Oct 2005, pp. 409-414.
Shekelle PG, Morton SC, Suttorp MJ, Buscemi N, Friesen C. Challenges in Systematic Reviews of Complementary and Alternative Medicine Topics, Annals of Internal Medicine, Vol. 142, No. 12, [Part 2], June 21 2005, pp. 1042-1045, W216-W248.
Whitlock EP, Lin JS, Chou R, Shekelle P, Robinson KA. Using Existing Systematic Reviews in Complex Systematic Reviews. Annals of Internal Medicine, Vol. 148, No. 10, May 20 2008, pp. 776-782
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