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A Review of the Scientific Literature As It Pertains to Gulf War Illnesses
Volume 2: Pyridostigmine Bromide
The United States and its allies in the Persian Gulf War (PGW) knew that Iraq had used nerve agents and chemical weapons in its previous conflicts and so took steps to protect their troops. Pyridostigmine bromide (PB) was distributed as a pretreatment that would enhance the effectiveness of postexposure treatments in the event that the nerve agent soman was used. This report examines the role that PB played in the ongoing chronic health problems documented in PGW veterans. After careful examination of the known effects of PB on the central and peripheral nervous systems, the author finds the evidence consistent with a possible role for PB as a contributor to the health complaints of some PGW veterans and calls for immediate attention in the form of additional investigation to clarify the role of PB.
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Executive Summary
Research Brief
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Paperback Cover Price: $30.00
Discounted Web Price: $27.00
Pages: 399
ISBN/EAN: 0-8330-2677-1
Contents
Chapter One:
Introduction PDF | HTML
Chapter Two:
Fact Sheet: PB Pretreatment for Soman Exposure PDF | HTML
Chapter Three:
Characteristics of PB PDF | HTML
Chapter Four:
PB Use in the Persian Gulf War PDF | HTML
Chapter Five:
Health Problems in PGW Veterans PDF | HTML
Chapter Six:
Theories Linking PB to Illness in Pgw Veterans PDF | HTML
Chapter Seven:
Blood-Brain Barrier Passage PDF | HTML
Chapter Eight:
Individual Differences in Reactions to PB PDF | HTML
Chapter Nine:
Interactions Between PB and Other Exposures PDF | HTML
Chapter Ten:
Bromism PDF | HTML
Chapter Eleven:
Multiple Chemical Sensitivity PDF | HTML
Chapter Twelve:
Neuromuscular Junction Effects PDF | HTML
Chapter Thirteen:
Neurotransmitter Dysregulation PDF | HTML
Chapter Fourteen:
Chronic Effects PDF | HTML
Chapter Fifteen:
Other Considerations PDF | HTML
Chapter Sixteen:
Conclusions PDF | HTML
Addendum: Evidence for Neurotransmitter Dysregulation Identified or Published Since the Review Process PDF | HTML
Appendix A:
Pyridostigmine Pharmacokinetic Data PDF | HTML
Appendix B:
Effects of PB in Humans PDF | HTML
Appendix C:
Further Discussion of the Acetylcholine-Serotonin Relationship PDF | HTML
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