| Condition-Related Topic Area | Corresponding Consumer-Oriented Questions | Number of Clinical Elements Used for Assessing Coverage and Accuracy per Topic Area |
| Breast Cancer | ||
| 1. Risk assessment | Are there any medications I can take to reduce my risk of getting breast cancer? | 2 |
| 2. Screening | No one in my family has had breast cancer. Do I still need breast exams and mammograms? When should I start having regular mammograms? Do I need one every year? | 4 |
| 3. Evaluation of a palpable breast Mass | I have a lump in my breast. What should be done to check this? | 4 |
| 4. Treatment | If I have Stage I or Stage II breast cancer, which is better treatment: mastectomy or lumpectomy plus radiation? Where can I get information about breast cancer clinical trials? | 4 |
| 5. Alternative therapies | What alternative therapies (such as acupuncture, herbs or homeopathy) can help me fight breast cancer? | 3 |
| Total Number of Condition-Related Clinical Elements for this Condition | 17 | |
| Condition-Related Topic Area | Corresponding Consumer-Oriented Questions | Number of Clinical Elements Used for Assessing Coverage and Accuracy per Topic Area |
| Depression | ||
| 1. Symptoms | I've been feeling a little sad lately. How do I know if I'm depressed? | 4 |
| 2. Treatment | What are the most effective treatments for depression? | 3 |
| 3. Antidepressant medications | If my doctor recommends an antidepressant medication for the treatment of my depression, how long should I take it for? What should I expect and when will I start to feel better? | 4 |
| 4. Role of Counseling | When should I consider psychological counseling instead of or in addition to medication? | 3 |
| 5. Suicidal ideation | I feel so depressed I've thought about suicide. What should I do? | 2 |
| 6. Evaluation | Who should I see for evaluation and treatment of my depression? A primary care doctor, a psychiatrist or a psychologist/therapist? | 4 |
| 7. Etiology | What causes depression? | 1 |
| Total Number of Condition-Related Clinical Elements for this Condition | 21 | |
| Condition-Related Topic Area | Corresponding Consumer-Oriented Questions | Number of Clinical Elements Used for Assessing Coverage and Accuracy per Topic Area |
| Childhood Asthma | ||
| 1. Symptoms | What are the common symptoms of asthma in children? | 4 |
| 2. Uncontrolled asthma | I have been told by a doctor that my child has asthma. S/he has difficulty breathing at night and uses an inhaler everyday. Does this mean that my child's asthma is not well controlled? | 2 |
| 3. Therapeutic modalities & side effects | What should I do about my child's asthma, especially if it is not well controlled? Are there any medicines or special equipment that my doctor can prescribe? Do they have any side effects? | 8 |
| 4. Symptoms | How do I know if my child is having life-threatening symptoms? What should I do? | 4 |
| 5. Risk factors | Could certain exposures in the indoor and/or outdoor environment have caused or made my child's asthma worse? What can be done to identify, eliminate or diminish factors in the environment that can worsen my child's asthma symptoms? | 7 |
| 6. Etiology | What causes asthma? Is it curable? | 4 |
| 7. Expectations from therapy | What should I expect from my child's asthma treatment? | 3 |
| Total Number of Condition-Related Clinical Elements for this Condition | 32 | |
| Condition-Related Topic Area | Corresponding Consumer-Oriented Questions | Number of Clinical Elements Used for Assessing Coverage and Accuracy per Topic Area |
| Obesity | ||
| 1. Indications for weight loss | How do I know if I need to lose weight? | 6 |
| 2. Risks | What are the health risks of being overweight/obese? | 4 |
| 3. Therapies | What should I consider before starting on a low carbohydrate, high protein, high fat diet like the Atkins plan? | 3 |
| 4. Prevention | What is the value of physical activity for a) promoting weight loss, b) maintaining weight at current levels, and c) for general health? | 4 |
| 5. Availability of drugs approved for weight loss | Should I consider weight-loss drugs, and if so, what prescription and non-prescription drugs are currently available? | 4 |
| 6. Treatment | Who should consider weight loss surgery, what are the risks, and how well does it work? | 6 |
| 7. Safety and effectiveness of dietary supplements containing ephedra plus caffeine | Can herbal supplements containing ephedrine plus caffeine help me to safely lose weight? | 3 |
| Total Number of Condition-Related Clinical Elements for this Condition | 30 | |