Cover: The In Vivo Adherence Intervention for at Risk Adolescents with Asthma

The In Vivo Adherence Intervention for at Risk Adolescents with Asthma

Report of a Randomized Pilot Trial

Published in: Journal of Pediatric Psychology, v. 37, no. 4, May 2012, p. 390-403

by Michael Seid, Elizabeth J. D'Amico, James W. Varni, Jennifer K Munafo, Maria T Britto, Carolyn M Kercsmar, Dennis Drotar, Eileen C King, Lynn Darbie

Read More

Access further information on this document at Journal of Pediatric Psychology

This article was published outside of RAND. The full text of the article can be found at the link above.

Abstract

OBJECTIVE: Low-income and minority adolescents are at high risk for poor asthma outcomes, due in part to adherence. We tested acceptability, feasibility, and effect sizes of an adherence intervention for low socioeconomic status (SES) minority youth with moderate- and severe-persistent asthma. DESIGN AND METHODS: Single-site randomized pilot trial: intervention (n = 12; asthma education, motivational interviewing, problem-solving skills training, 1 month cell-phone with tailored text messaging) versus control (n = 14; asthma education; cell-phone without tailored messaging). Calculated effect-sizes of relative change from baseline (1 and 3 months). RESULTS: Intervention was judged acceptable and feasible by participants. Participants (12–18 years, mean = 15.1, SD = 1.67) were 76.9% African-American, 80.7% public/no insurance. At 1 and 3 months, asthma symptoms (Cohen's d's = 0.40, 0.96) and HRQOL (PedsQL TM ; Cohen's d's = 0.23, 1.25) had clinically meaningful medium to large effect sizes. CONCLUSIONS: This intervention appears promising for at-risk youth with moderate- and severe-persistent asthma.

Research conducted by

This report is part of the RAND Corporation external publication series. Many RAND studies are published in peer-reviewed scholarly journals, as chapters in commercial books, or as documents published by other organizations.

The RAND Corporation is a nonprofit institution that helps improve policy and decisionmaking through research and analysis. RAND's publications do not necessarily reflect the opinions of its research clients and sponsors.