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A Review of Recent Advances in Knowledge About Methadone Maintenance Treatment

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By: Ineke van Beusekom, Martin Y. Iguchi

This report, which provides a knowledge base for the development of methadone maintenance treatment clinical guidelines in Switzerland, reviews the world-wide literature (except for Switzerland, which is the subject of a separate investigation) on such treatment and existing guidelines. Articles on methadone maintenance treatment and concurring treatment modalities are discussed in detail, as well as existing knowledge about specific populations, such as pregnant addicts and addicts with HIV or tuberculosis. Research on prognostic factors to patients' responses to treatment and perceptions of opiate dependent persons are also reviewed to ascertain their value to practitioners in managing methadone maintenance treatment and in assessing the best possible treatment. A final chapter describes other substitution treatments in comparison to methadone maintenance and synthesizes the information of the review into a structured information source for thinking about guideline development.

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Pages: 116

ISBN/EAN: 0-8330-3091-4

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Contents

Chapter One:
Introduction

Chapter Two:
Study Design

Chapter Three:
Guidelines and Clinical Practice Recommendations

Chapter Four:
Methadone - Characteristics of the Drug

Chapter Five:
Treatment Outcome Studies

Chapter Six:
Special Populations

Chapter Seven:
Studies Describing Psychosocial and Other Non-Pharmacological Aspects of Treatment

Chapter Eight:
Perceptions of Addicts of Methadone Maintenance Treatment

Chapter Nine:
Methadone Maintenance Treatment As Compared to Other Substitution Treatments

Chapter Ten:
Conclusions: Recommendations for Guideline Development

The research described in this report was performed within RAND Europe and RAND's Drug Policy Research Center.

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