Case Studies of Existing Human Tissue Repositories
"Best Practices" for a Biospecimen Resource for the Genomic and Proteomic Era
The National Biospecimen Network (NBN) Design Team, part of the Tissue Access Working Group convened by the National Dialogue on Cancer, is drafting a blueprint for a high-quality biospecimen network of biological sample banks. To assist in this effort, RAND has conducted case studies of twelve existing human tissue repositories to evaluate their utility for genomics- and proteomics-based cancer research and to identify “best practices” necessary for establishing a national tissue resource and data bank to optimize and accelerate genomics- and proteomics-based research. This monograph presents the findings for each repository evaluated. It addresses biospecimen collection, processing, annotation, storage, and distribution; bioinformatics; consumer and user needs; business plans and operations; privacy, ethical concerns, and consent issues; intellectual property rights and legal issues; and public relations, marketing, and education. All of the repositories evaluated exhibit some of the characteristics that would be useful for an NBN, but some incorporate more of the requirements than others do. Whether the Design Team decides to build a new repository or use existing institutions to create a national network, information gained from existing repositories provides important insights.
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Document Details
- Copyright: RAND Corporation
- Availability: Available
- Print Format: Paperback
- Paperback Pages: 246
- List Price: $27.50
- Paperback Price: $22.00
- Paperback ISBN/EAN: 0-8330-3527-4
- Document Number: MG-120-NDC/NCI
- Year: 2003
- Series: Monographs
Contents
Chapter One
Introduction
Chapter Two
Methodology
Chapter Three
Biospecimen Collection, Processing, Annotation, Storage, and Distribution
Chapter Four
Bioinformatics and Data Management
Chapter Five
Consumer/User Needs
Chapter Six
Business Plan and Operations
Chapter Seven
Privacy, Ethical Concerns, and Consent Issues
Chapter Eight
Intellectual Property and Legal Issues
Chapter Nine
Public Relations, Marketing, and Education
Chapter Ten
Findings and Summary of Best Practices
Appendix
Interview Instrument for RAND Evaluation of Existing Tissue Resources
The research described in this report was conducted by RAND Science and Technology for the National Cancer Institute and National Dialogue on Cancer.
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