Download eBook for Free

FormatFile SizeNotes
PDF file 1.5 MB

Use Adobe Acrobat Reader version 7.0 or higher for the best experience.

The independent Review on AMR led by the economist Jim O'Neill commissioned RAND Europe to conduct a study estimating the global costs of antimicrobial resistance until 2050 in the absence of any progress in tackling the challenge. We developed a general equilibrium model, which calculated the extent of losses to the world economy caused by decreases in the supply of labour resulting from resistant hospital acquired infections and selected major infectious diseases (HIV, TB, malaria). Our approach incorporated a set of seven scenarios with varying rates of future resistance, time of onset of increases in resistance, and availability of effective second-line therapy.

Table of Contents

  • Chapter One


  • Chapter Two

    Conceptual approach and scope of the study

  • Chapter Three

    Method: A dynamic general equilibrium model

  • Chapter Four

    Applying the theoretical model to AMR

  • Chapter Five


  • Chapter Six

    Sensitivity analyses and additional calculations

  • Chapter Seven


  • Chapter Eight


  • Appendix A

    Regional groupings

  • Appendix B

    Detailed discussion of health data components

  • Appendix C

    Detailed description of the economic data: social accounting matrix

  • Appendix D

    Summary of assumptions and limitations

Research conducted by

The research described in this report was prepared for the Independent Review on Antimicrobial Resistance and conducted by RAND Europe.

This report is part of the RAND Corporation research report series. RAND reports present research findings and objective analysis that address the challenges facing the public and private sectors. All RAND reports undergo rigorous peer review to ensure high standards for research quality and objectivity.

Permission is given to duplicate this electronic document for personal use only, as long as it is unaltered and complete. Copies may not be duplicated for commercial purposes. Unauthorized posting of RAND PDFs to a non-RAND Web site is prohibited. RAND PDFs are protected under copyright law. For information on reprint and linking permissions, please visit the RAND Permissions page.

The RAND Corporation is a nonprofit institution that helps improve policy and decisionmaking through research and analysis. RAND's publications do not necessarily reflect the opinions of its research clients and sponsors.