Depression

Untreated clinical depression and other mental illnesses can result in serious consequences for individuals, families, and society. RAND research seeks to optimize the use of effective treatments for depression whether in a primary care setting or by psychiatric professionals, and to understand the impact of depressive disorders on various populations, including new mothers, teens, substance abusers, and those with other illnesses such as HIV/AIDS or post-traumatic stress disorder (PTSD).

Research conducted by: RAND Health; RAND National Security Research Division; RAND Gulf States Policy Institute; Invisible Wounds of War Project

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Allegheny County Maternal Depression and Child Health Care Initiative

The Allegheny County Maternal Depression and Child Health Care Initiative helped to promote healthy lifestyles and positive health outcomes, reduce preventable disease and environmental health risks, eliminate health disparities, and ensure access to quality care for young children, mothers, and families.

Journal Articles (249)

Effects of Pain and Prescription Opioid Use on Outcomes in a Collaborative Care Intervention for Anxiety — Jan 1, 2013

Anxious patients with pain benefit as much as those without pain from cognitive-behavioral therapy and medication treatment.

An Implementation Evaluation of the Community Engagement and Planning Intervention in the CPIC Depression Care Improvement Trial — Jan 1, 2013

The goal of this paper is to document and evaluate the process of implementing an evidence-based depression intervention in community settings through the use of community-academic partnered approaches.

Diagnostic Overlap of Generalized Anxiety Disorder and Major Depressive Disorder in a Primary Care Sample — Dec 1, 2012

This study addresses the symptom overlap of people meeting DSM-IV-TR diagnostic criteria for GAD, MDD, or both to investigate whether comorbidity might be explained by overlapping diagnostic criteria.

Effects of Co-Occurring Depression on Treatment for Anxiety Disorders: Analysis of Outcomes from a Large Primary Care Effectiveness Trial — Dec 1, 2012

Co-occurring depression is common in patients seeking treatment for anxiety; however, the literature on the effects of depression on anxiety treatment outcomes is inconclusive.

Depression and Its Relationship to Work Status and Income Among HIV Clients in Uganda — Sep 1, 2012

Despite high levels of depression among persons living with HIV (PLWHIV), little research has investigated the relationship of depression to work status and income in PLWHIV in sub-Saharan Africa, which was the focus of this analysis.

Enhancing Cross-System Collaboration for Caregivers at Risk for Depression — Aug 1, 2012

In the United States, many health care systems function independently from one another. Increasing coordination across systems has the potential to vastly improve services and patient outcomes, yet implementing these changes can be challenging, requiring increased communication, interaction, and coordination across systems that typically function independently.

Relationships Between Mood and Employment Over Time Among Depressed VA Primary Care Patients — Jul 6, 2012

Veterans being treated for depression were more likely to become employed, and remain employed when their depression status improved, highlighting the need to prevent socioeconomic deterioration among working-aged veterans of Operation Enduring Freedom and Operation Iraqi Freedom.

Group Cognitive-Behavioral Therapy for Clients with Major Depression in Residential Substance Abuse Treatment — Jun 1, 2012

Group cognitive behavioral therapy was an effective treatment for major depression for clients in residential substance abuse treatment, thus extending the effectiveness of group CBT for major depression to a new setting, patient population, and type of provider.

Executive Functioning, Cortisol Reactivity, and Symptoms of Psychopathology in Girls with Premature Adrenarche — Feb 1, 2012

The study examined the interaction between early maturational timing (measured by premature adrenarche [PA]) and executive functioning and cortisol reactivity on symptoms of psychopathology.

A Population-Based Survey of Mental Disorders in Singapore — Feb 1, 2012

Mental illnesses are not only a growing public health concern but also a major social and economic issue affecting individuals and families throughout the world.

The Moderating Effects of Group Cognitive–behavioral Therapy for Depression Among Substance Users — Jan 1, 2012

This study examined the prospective longitudinal relationship between changes in depressive symptoms on alcohol and or drug use among addiction participants in treatment, and whether group cognitive-behavioral therapy for depression (GCBT-D) moderated the relationship.

Treating Depression and Substance Use: A Randomized Controlled Trial — Jan 1, 2012

To meet the call for more "transportable" interventions, the authors conducted a pilot study to test a group cognitive–behavioral therapy (CBT) for depression and substance use that was designed for delivery by outpatient substance abuse treatment counselors.

Assessment and Management of Patients with Cognitive Impairment and Dementia in Primary Care — Jan 1, 2012

Findings from this small study should be replicated in larger studies to stimulate interventions that will improve the initial and ongoing treatment of older persons with cognitive impairment.

Depression Treatment Preferences of Older White and Mexican Origin Men — Jan 1, 2012

Among older white and Mexican origin male primary care patients, we examined preferences for features of depression care programs that would encourage depressed older men to enter and remain in treatment.

Do Client Attributes Moderate the Effectiveness of a Group Cognitive Behavioral Therapy for Depression in Addiction Treatment? — Jan 1, 2012

The study goal was to determine whether client attributes were associated with outcomes from group cognitive behavioral therapy for depression (GCBT-D) as delivered in community-based addiction treatment settings.

The Quality of Mental Health Care for Veterans of Operation Enduring Freedom/Operation Iraqi Freedom — Jan 1, 2012

Efforts to maintain and/or increase OEF/OIF veteran participation in VA MH/SUD services should be informed by their characteristics, such as younger age and better physical health relative to other veterans.

Bayesian Hierarchical Semiparametric Modelling of Longitudinal Post-Treatment Outcomes from Open Enrolment Therapy Groups — Jan 1, 2012

There are several challenges to testing the effectiveness of group-therapy-based interventions in alcohol and other drug use treatment settings.

The Influence of Mental Disorders on School Dropout in Mexico — Nov 1, 2011

Studies the impact of mental disorders on failure in educational attainment in Mexico.

Implementing collaborative care for depression treatment in primary care: A cluster randomized evaluation of a quality improvement practice redesign — Oct 1, 2011

Collaborative care models for depression designed and implemented by VA primary care practices using evidence based quality improvement increased patients' use of antidepressants.

Building Capacity for Cognitive Behavioral Therapy Delivery for Depression in Disaster-Impacted Contexts — Jun 1, 2011

Lessons learned from this model of implementation may help address barriers to disseminating evidence-based interventions in other low-resource, disaster-impacted community settings.

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