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     <title>RAND Research Topic: Gastrointestinal Disorders</title>
     <link rel="self" href="http://www.rand.org/topics/gastrointestinal-disorders.xml"/>
     <updated>2012-05-24T14:17:07Z</updated>
     <link rel="alternate" type="text/html" hreflang="en" href="http://www.rand.org/topics/gastrointestinal-disorders.html" />
     <rights>Copyright (c) 2012, The RAND Corporation</rights>
     <author>
       <name>RAND Corporation</name>
     </author>
     <id>http://www.rand.org/topics/gastrointestinal-disorders.html</id>
	 
 <entry>
   <title type="html">Probiotics Can Reduce Risk of Diarrhea Caused by Antibiotics</title>
   <id>http://www.rand.org/pubs/external_publications/EP201200103.html</id>
   <published>May 8, 2012</published>
   <updated>May 8, 2012</updated>
   <summary type="html">Probiotics are believed to improve health by maintaining a normal balance of microorganisms in the human intestines. Evidence shows that they can reduce the risk of developing diarrhea, which is a common side effect of taking antibiotics.</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP201200103.html" />
   
 </entry>
 
 <entry>
   <title type="html">Probiotics Can Reduce Risk of Diarrhea Caused by Antibiotics</title>
   <id>http://www.rand.org/news/press/2012/05/08.html</id>
   <published>May 8, 2012</published>
   <updated>May 8, 2012</updated>
   <summary type="html">Probiotics are believed to improve health by maintaining a normal balance of microorganisms in the human intestines. Evidence shows that they can reduce the risk of developing diarrhea, which is a common side effect of taking antibiotics.</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/news/press/2012/05/08.html" />
   
 </entry>
 
 <entry>
   <title type="html">Eliminating Discretionary Use of Anesthesia Providers During Gastroenterology Procedures Could Generate $1.1 Billion in Savings per Year</title>
   <id>http://www.rand.org/pubs/research_briefs/RB9648.html</id>
   <published>Mar 20, 2012</published>
   <updated>Mar 20, 2012</updated>
   <summary type="html">The use of dedicated anesthesia providers for routine gastroenterology (GI) procedures is seen as medically justifiable only for high-risk patients. Eliminating these services for low-risk patients could generate $1.1 billion in savings per year.</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/research_briefs/RB9648.html" />
   
 </entry>
 
 <entry>
   <title type="html">Use of Anesthesia Providers During Gastroenterology Procedures Has Increased Rapidly, but May Be Unneeded</title>
   <id>http://www.rand.org/pubs/external_publications/EP20120073.html</id>
   <published>Mar 20, 2012</published>
   <updated>Mar 20, 2012</updated>
   <summary type="html">The use of dedicated anesthesia providers for routine gastroenterology (GI) procedures is seen as medically justifiable only for high-risk patients. Eliminating these services for low-risk patients could generate $1.1 billion in savings per year.</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP20120073.html" />
   
 </entry>
 
 <entry>
   <title type="html">Use of Anesthesia Providers During Gastroenterology Procedures Has Increased Rapidly, but May Be Unneeded</title>
   <id>http://www.rand.org/news/press/2012/03/20.html</id>
   <published>Mar 20, 2012</published>
   <updated>Mar 20, 2012</updated>
   <summary type="html">Use of anesthesia providers to monitor sedation during screening colonoscopies and other outpatient gastroenterology procedures more than doubled from 2003 to 2009 in the United States, with most of the increase among low-risk patients who may not need this service.</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/news/press/2012/03/20.html" />
   
 </entry>
 
 <entry>
   <title type="html">Minimally Important Differences of the UCLA Scleroderma Clinical Trial Consortium Gastrointestinal Tract Instrument</title>
   <id>http://www.rand.org/pubs/external_publications/EP201100139.html</id>
   <published>Aug 31, 2011</published>
   <updated>Aug 31, 2011</updated>
   <summary type="html">This study provided minimally important difference (MID) estimates for the UCLA Scleroderma Clinical trial Consortium Gastrointestinal Tract 2.0 instrument. This information can aid in interpreting scale scores in future randomized controlled trials and observational studies.</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP201100139.html" />
   
 </entry>
 
 <entry>
   <title type="html">Changes in Diarrheal Disease and Treatment Among Brazilian Children from 1986 to 1996</title>
   <id>http://www.rand.org/pubs/external_publications/EP20110094.html</id>
   <published>Jan 31, 2011</published>
   <updated>Jan 31, 2011</updated>
   <summary type="html">This paper examines changes in diarrhea prevalence and treatment in Brazil between 1986 and 1996 and concludes that policies to prevent the disease should be targeted at disadvantaged socioeconomic groups.</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP20110094.html" />
   
 </entry>
 
 <entry>
   <title type="html">Validation of a Quality-of-Life Scale for Women with Bladder Pain Syndrome/interstitial Cystitis</title>
   <id>http://www.rand.org/pubs/external_publications/EP201100263.html</id>
   <published>Jan 1, 2011</published>
   <updated>Jan 1, 2011</updated>
   <summary type="html">This study seeks to validate a disease-specific scale to measure the impact of symptoms of bladder pain syndrome/interstitial cystitis (BPS/IC), a condition that affects up to 6.5% of US women.</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP201100263.html" />
   
 </entry>
 
 <entry>
   <title type="html">C Difficile Lessons: Getting to the Bottom of Complex Health Problems</title>
   <id>http://www.rand.org/pubs/external_publications/EP20091010.html</id>
   <published>Dec 31, 2008</published>
   <updated>Dec 31, 2008</updated>
   <summary type="html">&lt;p&gt;Lessons from the C difficile experience with wider health policy implications.&lt;/p&gt;</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP20091010.html" />
   
 </entry>
 
 <entry>
   <title type="html">Reducing Stunting Among Children: The Potential Contribution of Diagnostics</title>
   <id>http://www.rand.org/pubs/external_publications/EP20061121.html</id>
   <published>Dec 31, 2005</published>
   <updated>Dec 31, 2005</updated>
   <summary type="html">&lt;p&gt;Stunting affects ~ 147 million children in developing countries.&lt;/p&gt;</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP20061121.html" />
   
 </entry>
 
 <entry>
   <title type="html">Hospital Competition, Managed Care and Mortality After Hospitalization for Medical Conditions: Evidence from Three States</title>
   <id>http://www.rand.org/pubs/external_publications/EP20060630.html</id>
   <published>Dec 31, 2005</published>
   <updated>Dec 31, 2005</updated>
   <summary type="html">&lt;p&gt;Assesses the effect of hospital competition and HMO penetration on mortality after hospitalization for six medical conditions in California, New York, and Wisconsin.&lt;/p&gt;</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP20060630.html" />
   
 </entry>
 
 <entry>
   <title type="html">Meta-analysis of Dyspepsia and Nonsteroidal Antiinflammatory Drugs</title>
   <id>http://www.rand.org/pubs/external_publications/EP20030815.html</id>
   <published>Dec 31, 2002</published>
   <updated>Dec 31, 2002</updated>
   <summary type="html">&lt;p&gt;Clinical trial data indicate that high dosages of any NSAID along with any dosage of indomethacin, meclofenamate, or piroxicam increase the risk of dyspepsia by about 3-fold&lt;/p&gt;</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP20030815.html" />
   
 </entry>
 
 <entry>
   <title type="html">A Metaanalysis of Severe Upper Gastrointestinal Complications of Nonsteroidal Antiinflammatory Drugs</title>
   <id>http://www.rand.org/pubs/external_publications/EP20021357.html</id>
   <published>Mar 31, 2002</published>
   <updated>Mar 31, 2002</updated>
   <summary type="html">&lt;p&gt;Prior metaanalyses of the risk of upper gastrointestinal (GI) complications associated with nonsteroidal antiinflammatory drugs (NSAID) have focused on the published English language epidemiologic literature and/or only a portion of the relevant evidence, restrictions that are now known to be associated with bias in metaanalysis. We synthesized the published and unpublished evidence to determine the least biased estimates of the risks of perforations, ulcers, and bleeds (PUB) associated with NSAID use from all study designs and all languages.&lt;/p&gt;</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP20021357.html" />
   
 </entry>
 
 <entry>
   <title type="html">Utilization of Health Care Resources for Low-Risk Patients with Acute, Nonvariceal Upper GI Hemorrhage: An Historical Cohort Study</title>
   <id>http://www.rand.org/pubs/external_publications/EP20020313.html</id>
   <published>Dec 31, 2001</published>
   <updated>Dec 31, 2001</updated>
   <summary type="html">&lt;p&gt;Adults hospitalized with acute, nonvariceal upper GI hemorrhage can be accurately stratified according to their risk of subsequent adverse outcomes by using the Rockall score.&lt;/p&gt;</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP20020313.html" />
   
 </entry>
 
 <entry>
   <title type="html">The Impact of Irritable Bowel Syndrome on Health-Related Quality of Life</title>
   <id>http://www.rand.org/pubs/external_publications/EP20000908.html</id>
   <published>Dec 31, 1999</published>
   <updated>Dec 31, 1999</updated>
   <summary type="html">&lt;p&gt;Few data are available to evaluate health-related quality of life (HRQOL) of people with irritable bowel syndrome (IBS).&lt;/p&gt;</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP20000908.html" />
   
 </entry>
 
 <entry>
   <title type="html">Is the Diagnostic Yield of Upper GI Endoscopy Improved By the Use of Explicit Panel-Based Appropriateness Criteria?</title>
   <id>http://www.rand.org/pubs/external_publications/EP20000904.html</id>
   <published>Dec 31, 1999</published>
   <updated>Dec 31, 1999</updated>
   <summary type="html">&lt;p&gt;Upper GI endoscopies performed for appropriate indications resulted in detecting significantly more clinically relevant lesions than did those performed for inappropriate indications.&lt;/p&gt;</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP20000904.html" />
   
 </entry>
 
 <entry>
   <title type="html">Overuse and Underuse of Colonoscopy in a European Primary Care Setting</title>
   <id>http://www.rand.org/pubs/external_publications/EP20001109.html</id>
   <published>Dec 31, 1999</published>
   <updated>Dec 31, 1999</updated>
   <summary type="html">&lt;p&gt;To improve quality of care, both overuse and underuse of important procedures must be addressed.&lt;/p&gt;</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP20001109.html" />
   
 </entry>
 
 <entry>
   <title type="html">Underutilization of Upper Gastrointestinal Endoscopy</title>
   <id>http://www.rand.org/pubs/external_publications/EP19970308.html</id>
   <published>Dec 31, 1996</published>
   <updated>Dec 31, 1996</updated>
   <summary type="html">&lt;p&gt;This article is a companion piece to the preceding article and looks at underuse of upper gastrointestinal endoscopy in the same 8,000 visits and over 600 patients who complained of upper digestive symptoms.&lt;/p&gt;</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP19970308.html" />
   
 </entry>
 
 <entry>
   <title type="html">Appropriateness of Upper GI Endoscopy: Comparison of American and Swiss Criteria</title>
   <id>http://www.rand.org/pubs/external_publications/EP19970021.html</id>
   <published>Dec 31, 1996</published>
   <updated>Dec 31, 1996</updated>
   <summary type="html">&lt;p&gt;Compares the development of appropriateness criteria for upper gastrointestinal endoscopy in the United States and in Switzerland.&lt;/p&gt;</summary>
   <link rel="alternate" type="text/xhtml" hreflang="en" title="Read More" href="http://www.rand.org/pubs/external_publications/EP19970021.html" />
   
 </entry>
 
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