RAND Research Topic: Genetics2012-05-24T14:13:49ZCopyright (c) 2012, The RAND CorporationRAND Corporationhttp://www.rand.org/topics/genetics.htmlDiagnostics as Essential Tools for Containing Antibacterial Resistancehttp://www.rand.org/pubs/external_publications/EP201100122.htmlMar 31, 2011Mar 31, 2011Appropriate use of existing diagnostic tests for infections, and development of better ones, could reduce overuse of antibacterial drugs.Are Electronic Health Records Ready for Genomic Medicine?http://www.rand.org/pubs/external_publications/EP20090715.htmlJun 30, 2009Jun 30, 2009<p>The goal of this project was to assess genetic/genomic content in electronic health records.</p>Delivery of Genomic Medicine for Common Chronic Adult Diseaseshttp://www.rand.org/pubs/research_briefs/RB9338.htmlApr 2, 2008Apr 2, 2008<p>This fact sheet summarizes recommendations for health care workers, consumers, and the scientific community to prepare the health care system for genomic medicine for common chronic diseases.</p>Health Professionals and the Public Unprepared to Make Use of Genomic Medicine for Adultshttp://www.rand.org/news/press/2008/03/18.htmlMar 18, 2008Mar 18, 2008<p>Although advances in genomic medicine for common adult chronic diseases such as heart disease, diabetes, and cancer hold promise for improved prevention, diagnosis and treatment, health professionals and the public are not prepared to effectively integrate these new tools into practice.</p>Delivery of Genomic Medicine for Common Chronic Adult Diseases: A Systematic Reviewhttp://www.rand.org/pubs/external_publications/EP20080315.htmlDec 31, 2007Dec 31, 2007<p>Synthesizes current information on genetic health services for common adult-onset conditions by examining studies that have addressed the outcomes, consumer information needs, delivery, and challenges in integrating these services.</p>Relation of Familial Patterns of Coronary Heart Disease, Stroke, and Diabetes to Subclinical Atherosclerosis: The Multi-Ethnic Study of Atherosclerosishttp://www.rand.org/pubs/external_publications/EP20081223.htmlDec 31, 2007Dec 31, 2007<p>Investigate the possibility that family history beyond early-onset coronary heart disease might contribute to coronary heart disease susceptibility, the authors studied associations between additional family history and the coronary artery calcium score.</p>Haplotypes in the Lipoprotein Lipase Gene Influence High-Density Lipoprotein Cholesterol Response to Statin Therapy and Progression of Atherosclerosis in Coronary Artery Bypass Graftshttp://www.rand.org/pubs/external_publications/EP20070212.htmlJan 31, 2007Jan 31, 2007<p>Lipoprotein lipase (LPL) hydrolyzes circulating triglycerides (TGs). We previously showed that 3'-end haplotypes in the LPL gene influence atherosclerosis and insulin resistance. This study asked whether these LPL haplotypes influence response to lipid-lowering therapy among 829 subjects from the Post-Coronary Artery Bypass Graft trial. Lipid profiles were obtained at baseline and 4-5 years after treatment with lovastatin.</p>Efficacy of Angiotensin-Converting Enzyme Inhibitors and Beta-Blockers in the Management of Left Ventricular Systolic Dysfunction According to Race, Gender and Diabetic Status: A Meta-Analysis of Major Clinical Trialshttp://www.rand.org/pubs/external_publications/EP20030513.htmlDec 31, 2002Dec 31, 2002<p>Women with asymptomatic LV systolic dysfunction may not achieve a mortality benefit when treated with ACE inhibitors.</p>Maren T. Scheunerhttp://www.rand.org/about/people/s/scheuner_maren_t.html<em>Affiliated Adjunct Staff</em><br>M.D., M.P.H., University of California, Los Angeles; B.S. in biology, University of California, Riverside