The Southern California Evidence-based Practice Center

The Southern California Evidence-based Practice Center (EPC) was established at RAND and resided there until 2019. The EPC was designated by the Agency for Healthcare Research and Quality (AHRQ) as one of 12 centers in North America to produce evidence reports.

The EPC reviewed scientific literature on a wide spectrum of clinical and health services topics. We produced systematic reviews, evidence maps, scoping reviews, rapid reviews, and other literature synthesis products. Our reviews informed clinicians, patients, guideline groups, policy makers, purchases, payors, and research agendas. We synthesized literature on medical, psychological, behavioral, and organizational topics and conduct research to advance evidence synthesis methods.

implementationnumberAHRQhealth carereviewresearchreportbasedRANDcenterinjuryJAMAfattylearninglifeliteraturelabelmachinemajordysfunctionmassmeasuresarthritisclosingmedicationmedicinemeditationaffairsassociationsefficiencymultipleneedolderephedraosteoarthritisosteoporosisepidemioloutcomespainatypicaleventspediatricspersonsphysicianspopulationposttraumaticcontextexpertexternalprimaryprobioticsfactorsfallsproviderpsychologicalbariatricfinancingfoodfracturesreducegoutadministrationresourcesguidancerheumatoidcoronaryrolebonecriteriasclerosisscreeningsearchsecurityHSR&Dsignalssitesmokingspinalstatedensitybrainsubstancesupplementalsupportwrongincreaseinflammatorydepressivetechnicalantioxidantsantipsychoticsthromboembolismapproachesadvancingjournalurinaryvalidityvenousveteranskneeweightwomenclinicmediaqualityotitisdrugomegapapersgrouprisklossacupunctureworkinformationmedicaretreatmentrapididentifyinghealthsafetymetaefficacyprogramprojectacutecaremethodsdisordereffectstechnologycostscancerevidencestudyprepareddepartmentacids

Our EPC combined the talents of RAND and our core collaborators at the University of California, Los Angeles; University of California, San Francisco; Stanford University; and University of Southern California. In addition, through the VA HSR&D Center of Innovation and the VA Evidence-Synthesis Program (ESP), we collaborated with the Greater Los Angeles Veteran Affairs Healthcare System. The center was also affiliated with five health services research training programs, and the Guidelines International Network.

RAND continues these lines of research through the Southern California Evidence Review Center, in partnership with the University of Southern California.