The UK government invests approximately £1.6 billion in medical research each year, and the British public donated £1.7 billion to medical research charities in 2012–13. This funding delivers health gains for patients and also benefits the UK economy at a 40 percent return annually.
RAND Europe and HERG were asked by UK medical research funders to investigate returns to public/charitable investment in cancer research. This report details the five case studies conducted as part of this work and observations emerging across them.
In many studies with a survival outcome, it is often not feasible to fully observe the primary event of interest. This often leads to heavy censoring and thus, difficulty in efficiently estimating survival or comparing survival rates between two groups.
There is widespread misuse of imaging tests in men with low-risk prostate cancer, particularly for CT. These findings highlight the need for examination of factors that drive decision making with respect to imaging in this setting.
At present, most patients who eventually undergo radical or partial nephrectomy do not undergo RMB, whereas most patients who eventually undergo ablation or systemic therapy do. The optimal use of RMB in the evaluation of kidney tumors has yet to be determined.
This study examined the association between socioeconomic status (SES) and obesity risk during early adolescence, ages 10–13 years, and whether this association is present in different racial/ethnic and gender groups during 2 time points in early adolescence.
Most medical research focuses on fighting individual disease. But delayed aging could boost life expectancy by more than two years and yield more than $7 trillion over 50 years. Greater investment in research to delay aging could be a very efficient way to prevent disease, improve public health, and extend healthy life.
Both practice environment and patient clinical and demographic characteristics are associated with cancer clinical trial enrollment; simultaneous intervention may be required when trying to increase enrollment rates.