Developing a conceptual framework for estimating the value of personalized medicines shows two sources of value: a market-expansion effect, and a market-contraction effect due to discontinuation of treatment by persons unresponsive to treatment.
New interventional cardiac catheterization services offered by U.S. hospitals generally duplicate existing programs and do not help patients gain access to timely emergency cardiac care. Instead, the focus has been on competing with other hospitals.
Calculating statins' social value reveals that consumers captured 76 percent of the total social value of the survival gains, with even greater consumer benefits expected in the future as prescribing rates rise and statin costs decrease.
Neighborhood socioeconomic status is significantly associated with coronary heart disease risk, according to a nationally-representative sample. The association is larger in men than women and in whites than minorities.
People who do shift work should be vigilant about their risk factors. At the same time, their employers—and the government—can do more to offer education and targeted screening programs to prevent or forestall disease, writes Christian van Stolk.
In this paper, we suggest approaching the estimation of risk factors on health with the use of a semi-parametric method and visualization for improvement of the threshold selection in variable dichotomization while accounting for mixture distributions in the outcome of interest and adjusting for covariates.
Current federal standards for hospital "meaningful use" of health information technology--which requires electronic medication orders for 30 percent of eligible patients--are probably too low to reduce deaths from heart failure and heart attack among hospitalized Medicare beneficiaries.
Project Retrosight analysed 29 case studies of cardiovascular and stroke research in Australia, Canada, and the UK, and found that clinical research has greater societal impact over a 15-20 year timescale, while basic research has greater academic impact.
Project Retrosight analysed 29 case studies of cardiovascular and stroke research in Australia, Canada and the UK, examining the diversity of impact produced by this kind of research and identifying factors associated with various levels of payback.
This work explores impacts of cardiovascular and stroke research funded 15–20 years ago and draws out aspects associated with high or low impact. It describes 29 case studies of grants from Australia, Canada and UK. Methodology volume.
Project Retrosight analyzed 29 case studies of cardiovascular and stroke research in Australia, Canada, and the UK, and found that clinical research has greater societal impact over a 15–20 year timescale, while basic research has greater academic impact.
There is little evidence of an association between short- or long-term exposure to particulate matter air pollution and venous thromboembolism; and no evidence that hormone therapy is modifing such a link.
Using surveillance data, researchers identified neighborhoods in a Georgia county with a persistently high incidence of cardiac arrest and low rates of bystander CPR. Such neighborhoods are promising targets for community-based interventions.