Genomic Medicine

Journal Article

The Value of Diagnostic Testing in Personalized Medicine

A framework derived from information economics for assessing the value of diagnostics demonstrates that the social value of such diagnostics can be very large, both by avoiding unnecessary treatment and by identifying patients who otherwise would not get treated.

Journal Article

Effective Communication of Molecular Genetic Test Results

Using a template for molecular genetic test reports, developed to reduce communication errors between the laboratory and ordering clinician, was found to improve physician ratings compared to standard laboratory templates—especially with doctors who were least familiar with the reports.

Commentary

What Will Change Most About Our Routine Physicals Over the Next Decade?

Don't forget—an American's odds of living a long and healthy life still depend more on his zip code than his genetic code. That won't change until we make healthcare more affordable, writes Dr. Arthur Kellermann.

Journal Article

A Report Template for Molecular Genetic Tests Designed to Improve Communication Between the Clinician and Laboratory

With input from key stakeholders and building upon prior work, we created a template for molecular genetic test reports designed to improve clinical decision making at the point of care.

Journal Article

Diagnostics as Essential Tools for Containing Antibacterial Resistance

Appropriate use of existing diagnostic tests for infections, and development of better ones, could reduce overuse of antibacterial drugs.

Journal Article

Population Prevalence of Familial Cancer and Common Hereditary Cancer Syndromes: The 2005 California Health Interview Survey

We provide population-based prevalence estimates for moderate and strong familial risk for five common cancers and hereditary breast-ovarian cancer and hereditary nonpolyposis colon cancer.

Journal Article

Are Electronic Health Records Ready for Genomic Medicine?

The goal of this project was to assess genetic/genomic content in electronic health records.

Research Brief

Delivery of Genomic Medicine for Common Chronic Adult Diseases

This fact sheet summarizes recommendations for health care workers, consumers, and the scientific community to prepare the health care system for genomic medicine for common chronic diseases.

News Release

Health Professionals and the Public Unprepared to Make Use of Genomic Medicine for Adults

Although advances in genomic medicine for common adult chronic diseases such as heart disease, diabetes, and cancer hold promise for improved prevention, diagnosis and treatment, health professionals and the public are not prepared to effectively integrate these new tools into practice.

Journal Article

Health Professionals and the Public Unprepared to Make Use of Genomic Medicine for Adults

Although advances in genomic medicine for common adult chronic diseases such as heart disease, diabetes, and cancer hold promise for improved prevention, diagnosis and treatment, health professionals and the public are not prepared to effectively integrate these new tools into practice.

Journal Article

Genomic Medicine: The Sorcerer's New Broom? the Limitations of the Human Genome Project

The author warns that genomic medicine runs the risk of diverting the attention of medicine away from what the public and its critics have been saying

Report

A Preliminary Model of Double-Minute-Mediated Gene Amplification

Develops a mathematical model of double minute (dm) population dynamics based on current concepts of the saltatory replication, random partitioning, nuclear exclusion and loss, and cellular growth inhibition of these extrachromosomal elements.

People

Denis Agniel

People

Sana Zakaria