Although overdose deaths from heroin and prescription opioids have declined, deaths involving synthetic opioids are on the rise. Much of the current wave of overdoses is linked to one synthetic opioid: fentanyl.
About half of all U.S. states now have policies that criminalize substance use during pregnancy, consider it grounds for civil commitment, or consider it child abuse or neglect. But research suggests that punitive policies aren't beneficial for infants or their mothers.
We review the change over time in state-level policy environments around substance use in pregnancy and contrast the policy response with the principles and guidance from professional societies and federal agencies.
A study examined the rates of hospitalisation or death related to severe bacteria infections among people who inject heroin in South London, England. The report compared these rates to the general population and calculated the cost of admissions.
This study found an increase in the rate of overdose after Medicare Part D coverage began to include benzodiazepines among adults aged 65 to 69 years and 80 years or older and an increase in the rate of fall-related injury in adults 80 years or older.
In the profitable buprenorphine market, pharmaceutical manufacturer Reckitt Benckiser exploited various Food and Drug Administration regulatory procedures to impede entry of generic competitors and maintain elevated prices.
State-level prescription drug monitoring programs that incorporate robust design features can significantly reduce the proportion of commercially insured adults who receive opioid prescriptions as well as the strength of those prescriptions.
Early evidence suggests that opioid duration limits had a variable association with postoperative opioid prescribing and should only be part of a larger, multifaceted effort to reduce excessive postoperative opioid prescribing.
In this article, the authors use the case of Suboxone to demonstrate egregious anti-competitive practices that delay generic entry, estimate the costs of these delays to the public, and suggest legislative and regulatory reforms to prevent these practices going forward.
Few people foresaw how quickly fentanyl would displace heroin, doubling or tripling opioid overdose deaths in some pockets of the United States from 2013 to 2017. But we could have been warned—if only we'd checked our wastewater.
Our study provides a snapshot of trends in the rate at which opioid therapy was initiated among commercially insured patients during a period of heightened attention to the dangers of opioids and the prominent release of prescribing guidelines by the CDC.
This weekly recap focuses on responding to Russian subversion, how the media can help fight Truth Decay, the first supervised drug consumption site in the United States, artificial intelligence, and more.