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RAND-USC Schaeffer OPTIC

A National Resource for Opioid Policy Science

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Note from the Co-Director

Beth Ann Griffin

The Biden Administration's plan to combat drug overdoses and the pending opioid settlement funds will give states funding to address the relentlessly evolving opioid crisis. But decisionmakers need to know whether a given policy will have the intended effect, for the target population, in their state.

An OPTIC team conducted an extensive simulation study to compare the statistical performance of commonly used methods for evaluating state-level opioid policies, including popular difference-in-differences (DID) methods. We found that DID models had low power to detect potentially actionable state-level policy effects and generated high false positive rates when examining state-level outcomes. As a result, policy evaluations using such approaches are likely to have findings that are inaccurate, inflated, and even in the wrong direction. Our simulations showed that autoregressive models outperformed DID models in terms of power, false positives, and directional bias, and we strongly encourage the field to consider such models in future policy evaluations. You can learn more about this work in our recent webinar series.

A recent useful addition to the OPTIC website is a STATA tool to help researchers determine whether they have a "good match" between a control group of states that has not implemented a policy with a treated group that has.

The entire OPTIC team wishes you a safe and productive new year. As always, we welcome your comments and suggestions at OPTIC@rand.org.

Stay safe. – Beth Ann Griffin, Co-Director OPTIC

Recent Products from OPTIC Researchers

Abstract data charts superimposed on each other, photo by Evorona/Getty Images

Photo by Evorona/Getty Images

Moving Beyond the Classic Difference-In-Differences Model: a Simulation Study Comparing Statistical Methods for Estimating Effectiveness of State-Level Policies

Researchers conducted an extensive simulation study to compare the statistical performance of commonly used methods for evaluating state-level opioid policies, including popular difference-in-differences methods. Read more »

Seated female therapist wearing a mask, holding a clipboard, and facing her client, photo by SDI Productions/Getty Images

Photo by SDI Productions/Getty Images

Assessment of State and Federal Health Policies for Opioid Use Disorder Treatment During the COVID-19 Pandemic and Beyond

Researchers summarize the multitude of ways access to and utilization of treatment for individuals with opioid use disorder (OUD) might have been expanded by state and federal policy during COVID-19 pandemic in 4 key areas: telehealth, privacy, licensing, and medication for OUD. Read more »

Gloved hand holding a vial of buprenorphine and a syringe, photo by Hailshadow/Getty Images

Photo by Hailshadow/Getty Images

Use of Buprenorphine for Those with Employer-Sponsored Insurance During the Initial Phase of the COVID-19 Pandemic

This study examined changes in the use of buprenorphine to treat opioid use disorder in 2020 during the onset of the COVID-19 pandemic using pharmaceutical claims.
Read more »

Mother holding her newborn baby in the hospital, photo by kieferpix/Getty Images

Photo by kieferpix/Getty Images

Neonatal Opioid Withdrawal Syndrome Is Associated With Infant Foster Care Entry At The County Level

This study used a decade of data from U.S. counties to examine how rates of neonatal opioid withdrawal syndrome (NOWS) and county-level characteristics were associated with entry in the child welfare system. Read more »

Close up of a person pouring prescription pills into a hand, photo by Rattankun Thongbun/Getty Images

Photo by Rattankun Thongbun/Getty Images

Claims-Based Measures of Prescription Opioid Utilization: A Practical Guide for Researchers

Researchers reviewed medical literature for recent studies that use claims data to construct opioid utilization measures, then developed a guide for researchers regarding opioid utilization measures and measure definitions, and how these may influence study results. Read more »

View All Publications »

Commentary and Press

Biden's Overdose Prevention Plan Faces Social, State Barriers (Bloomberg Law)

Fentanyl is one reason why the U.S. drug addiction crisis is roaring back (NPR Morning Edition)

New USC Schaeffer Research Maps State and Federal Responses to the Opioid Crisis During the COVID-19 Pandemic (USC Schaeffer)

Study shows link between neonatal opioid withdrawal syndrome and foster care entry (VUMC Reporter)

No states

have adopted a comprehensive policy package to expand access to OUD treatment during COVID-19.

(RAND Corporation)

National Perspectives

A national sampling of thought-provoking research and insights

A comparison of methods for measuring spatial access to health care - Drake C, et al. Health Serv Res

Broadening access to naloxone: Community predictors of standing order naloxone distribution in Massachusetts - Chatterjee A, et al. Drug Alcohol Depend

Characteristics and correlates of U.S. clinicians prescribing buprenorphine for opioid use disorder treatment using expanded authorities during the COVID-19 pandemic - Jones CM, et al. Drug Alcohol Depend

Experiences with substance use disorder treatment during the COVID-19 pandemic: Findings from a multistate survey - Saloner B, et al. Int J Drug Policy

Healthcare patterns of pregnant women and children affected by OUD in 9 state Medicaid populations - Jarlenski M, et al. JAMA Psychiatry

Initiating opioid use disorder medication via telemedicine during COVID-19: Implications for proposed reforms to the Ryan Haight Act - Huskamp HA, et al. J Gen Intern Med

Racial inequity in medication treatment for opioid use disorder: Exploring potential facilitators and barriers to use - Hollander MAG, et al. Drug and Alcohol Dependence

The impact of methamphetamine/amphetamine use on receipt and outcomes of medications for opioid use disorder: a systematic review - Frost MC, et al. Addict Sci Clin Pract

The role of stigma in U.S. primary care physicians' treatment of opioid use disorder - Stone EM, et al. Drug Alcohol Depend

Forthcoming Presentations

March 27, 2022
Presenting a panel session The Origins, Evolution and Consequences of the Opioid Epidemic at the Association for Public Policy Analysis & Management (APPAM) Conference - Rosanna Smart and Rosalie Pacula

Leadership

Brad Stein

Bradley Stein

Director

Rosalie Liccardo Pacula

Rosalie Liccardo Pacula

Codirector

Beth Ann Griffin

Beth Ann Griffin

Codirector

 

OPTIC is designed to be a national resource, fostering innovative and high-quality research in opioid policy science, and developing and disseminating methods, tools, and information to the research community, policymakers, and other stakeholders.

https://www.rand.org/OPTIC

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