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Note from the Co-Director

Beth Ann Griffin

The OPTIC Team is excited to announce release of the OPTIC Simulation Tool—the newest addition to OPTIC's body of public goods. The tool allows users to select from a range of simulation options to explore how different state policy evaluation methods perform on their own longitudinal data. The recent Difference-In-Differences (DID) literature revealed issues with traditional DID models, and there has been an explosion of new methods in this area for researchers to consider. We found it difficult to evaluate the relative performance of different causal inference methods using longitudinal outcome data on opioid mortality and prescribing rates. So we designed a series of simulations to study the performance of various methods under different scenarios for any type of repeated measures outcome data. In Griffin et al. (2021), we use real-world data on opioid mortality rates to assess commonly used DID designs. We identified notable limitations and some promising methods. In Griffin et al. (2022), we demonstrated the importance of controlling for the effects of occurring policies when examining policy effects. Our package can help you assess how co-occurring policies and confounding can affect the performance of statistical models commonly used in state policy evaluations.

The tool's introductory vignette provides a working example of how to use the package, based on the sample overdoses dataset provided with the package.

You will need R (>= 4.1.0) to use this package. You can install it from CRAN with install.packages ("optic") and then by typing library(optic).

Please feel free to share widely with your colleagues, and we always welcome your comments and suggestions at OPTIC@rand.org. – Beth Ann Griffin, Co-Director

Recent Products from OPTIC Researchers

Illustration of a program coding app with code, image by filo/Getty Images

Photo by filo/Getty Images

OPTIC Simulation Tool for Causal Inference Using Longitudinal Data

OPTIC researchers created this R package tool to help other researchers scrutinize candidate causal inference models using their own longitudinal data. Explore on rand.org » or Download on GitHub »

Prescription bottle of Oxycodone with white pills next to it, photo by Johnrob/Getty Images

Photo by Johnrob/Getty Images

Understanding the Rise in Overdose Deaths Involving Opioids and Non-Opioid Prescription Drugs in the United States

This paper studies how the reformulation of OxyContin led to the rise of polysubstance overdose deaths involving non-opioid prescription drugs. Read more »

Physician holding a prescription pill bottle in one hand and writing with the other,  photo by DragonImages/Getty Images

Photo by DragonImages/Getty Images

Exploring the Association of State Policies and the Trajectories of Buprenorphine Prescriber Patient Caseloads

Researchers conducted a retrospective cohort study to examine the relationship between state buprenorphine policies and clinicians' buprenorphine prescribing trajectories.
Read more »

Physician wearing a mask consults with an older man wearing a mask, photo by Dragos Condrea/Getty Images

Photo by Dragos Condrea/Getty Images

Trends in Methadone Dispensing for Opioid Use Disorder After Medicare Payment Policy Changes

A new Medicare policy may have improved access to methadone and buprenorphine treatment for Medicare beneficiaries with a diagnosed opioid use disorder (OUD) during the COVID-19 pandemic, but further research is needed to determine its impact. Read more »

Close up of a doctor taking notes in a class setting, photo by izusek/Getty Images

Photo by izusek/Getty Images

Association of Selected State Policies and Requirements for Buprenorphine Treatment with Per Capita Months of Treatment

State-mandated educational requirements beyond the initial training required to prescribe buprenorphine were associated with increased buprenorphine use over time. Read more »

Wooden blocks with people icons against a blue background and connected with white lines, photo by akinbostanci/Getty Images

Photo by akinbostanci/Getty Images

State Policy and the Breadth of Buprenorphine-Prescriber Networks in Medicaid Managed Care

Researchers used a diff-in-diff approach to compare three Medicaid Managed Care networks for buprenorphine providers across specialties and market segments within the same state. Read more »

Woman paying via credit card machine held by a staff person, photo by Jordi Mora Igual/Getty Images

Photo by Jordi Mora Igual/Getty Images

Prevalence of Buprenorphine Providers Requiring Cash Payment from Insured Women Seeking Opioid Use Disorder Treatment

Researchers used an audit (simulated patient) study methodology to examine appointment-granting behavior by buprenorphine prescribers in ten different U.S. states. Read more »

Doctor wearing a mask meets with a masked patient in a waiting room, photo by SDI Productions/Getty Images

Photo by SDI Productions/Getty Images

Buprenorphine Treatment Episodes During the First Year of COVID: A Retrospective Examination of Treatment Initiation and Retention

Buprenorphine treatment remained stable during the pandemic, however the flow of individuals receiving treatment changed significantly, indicating that policy efforts were successful in maintaining existing patients, but did not extend to new patients. Read more »

View All Publications »

Commentary and Press

State Policies Requiring Education for Buprenorphine Prescribers Boosts Use of Opioid Use Disorder Treatment (RAND Corporation)

Treatment for Opioid Use Disorder Rises After Medicare Expands Coverage for Methadone (RAND Corporation)

America's Opioid Crisis: Adopting an Ecosystem Approach (RAND Corporation)

U.S. Opioid Crisis Best Viewed as Connected Ecosystem; Changing Policymakers' Approach Can Aid Solutions (RAND Corporation)

Making Sense of Policy Evaluations for State Policymakers (Johns Hopkins Bloomberg School of Public Health)

Icon representing a hand taking cash. Illustration by Illustrator de la Monde/Getty Images

40% of prescribers

required that women with either Medicaid or private insurance pay out-of-pocket to receive an OUD treatment appointment.

(RAND Corporation)

National Perspectives

A national sampling of thought-provoking research and insights

Association of Receipt of Opioid Use Disorder-Related Telehealth Services and Medications for Opioid Use Disorder with Fatal Drug Overdoses Among Medicare Beneficiaries Before and During the COVID-19 Pandemic - Jones et al. JAMA Psychiatry

Association of Implementation of Postoverdose Outreach Programs With Subsequent Opioid Overdose Deaths Among Massachusetts Municipalities - Xuan et al. JAMA Psychiatry

Change in opioid and buprenorphine prescribers and prescriptions by specialty, 2016-2021 - Larochelle et al. Drug Alcohol Depend

Comparison of a national commercial pharmacy naloxone data source to state and city pharmacy naloxone data sources-Rhode Island, Massachusetts, and New York City, 2013-2019 - Chatterjee et al. Health Services Research

Effects of state opioid prescribing cap laws on providers' opioid prescribing patterns among patients with chronic non-cancer pain - Tormohlen et al. Prev Med

Estimated Reductions in Opioid Overdose Deaths with Sustainment of Public Health Interventions in 4 US States - Chhatwal et al. JAMA Network Open

Framing harm reduction as part of an integrated approach to reduce drug overdose: A randomized message testing experiment in a nationally representative sample of U.S. adults, 2022 - McGinty et al. International Journal of Drug Policy

Medicaid Expansion and Racial-Ethnic Health Care Coverage Disparities Among Low-Income Adults with Substance Use Disorders - Olfson et al. Psychiatr Serv

Medical Marijuana Access and Prolonged Opioid Use among Adolescents and Young Adults - Kim et al. Am J Addict

Measurement Approaches to Estimating Methadone Continuity in Opioid Use Disorder Care - Busch et al. Medical Care

Recreational cannabis and opioid distribution - Raman et al. Health Econ

Forthcoming Presentations

October 18, 2023
Leading a pre-conference workshop, Navigating the Myriad of Analytic Choices for Policy Evaluation Studies at the Addiction Health Services Research Conference - Rosanna Smart, Megan Schuler, and Beth Ann Griffin

Leadership

Brad Stein

Bradley Stein

Director

Rosalie Liccardo Pacula

Rosalie Liccardo Pacula

Codirector

Beth Ann Griffin

Beth Ann Griffin

Codirector

 

OPTIC is designed to be a national resource, fostering innovative and high-quality research in opioid policy science, and developing and disseminating methods, tools, and information to the research community, policymakers, and other stakeholders.

https://www.rand.org/OPTIC

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