Impact of Issuing Longer- Versus Shorter- Duration Prescriptions: A Systematic Review
14 Mar 2018
UK recommendations to provide shorter prescriptions are not substantiated by the current evidence base.
A review of clinical and economic evidence, followed by economic modelling, suggests that the NHS should rethink its policies and guidance promoting 28-day vs three-month prescription lengths.
Although a shorter prescription length may reduce medicine wastage, three-month prescriptions were associated with lower administrative costs and improved medication adherence among those with chronic illnesses.
In the British National Health Service, GPs have been encouraged to issue prescriptions of shorter duration, usually 28 days, to reduce drug expenditure and wastage.
There is some evidence to suggest that limiting prescription durations to 28 days results in cost savings by reducing wastage, but there is also some evidence to suggest that shorter prescriptions may increase costs through increased GP workloads and dispensing fees. Prescription length also has important implications for patient satisfaction, with evidence suggesting that patients prefer longer prescriptions.
Overall, the relative effectiveness and cost-effectiveness of shorter versus longer duration prescriptions is uncertain.
The aim of this review, commissioned by the NHS National Institute for Health Research, was to provide a high-quality reference on the clinical and cost-effectiveness of 3 month vs 28 days prescriptions in patients with stable chronic diseases. Specifically, the research team aimed to evaluate the impact of prescription length on disease-specific measurements, drug wastage, adverse events, patient experience and satisfaction, administration time, pharmacist costs and health outcomes.
This study involved three stages. The first two stages consisted of a review of the clinical and economic evidence of the effectiveness and cost-effectiveness of different prescription lengths. The third stage involved economic modelling of the net cost to the NHS from changes in drug wastage, dispensing fees and GP time as a result of the 28-day compared to three-month prescriptions, as well as an estimate of health gains.