Modeling the Economic Benefits of Malaria Control in Sub-Saharan Africa

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Researchers developed a computable general equilibrium model to help understand the economic benefits of malaria control in Ghana, as well as the role that health investments can play in stimulating growth in developing countries and to improve health policies.

The study found that investing in malaria vaccination for children not only helps in reducing malaria cases and deaths, it could also have long term macroeconomic benefits when these children enter the workforce as adults.


According to the World Health Organisation (WHO), there are nearly half a billion cases of malaria annually worldwide, with children under the age of five being particularly at risk. Not only does this cause a significant health problem in some parts of the world, it also carries a huge burden that impairs economic and social development in these areas. This means that reducing the prevalence of malaria through a large-scale prevention programme has the potential to contribute considerably to sustainable economic development in the region.

Measuring the relationship between health interventions, such as malaria prevention, and economic outcomes is particularly challenging because the links between public health and economic systems are complex. A computable general equilibrium (CGE) model is an approach that takes into account the many interactions throughout an economy and allows for more reliable measurement of economic outcomes.


Research Questions

  1. What is the relation between reducing malaria prevalence and economic growth?
  2. What are the distributional implications? Alongside the average effect, what happens to the lowest income group and the highest income group?
  3. How do those effects evolve over time?
  4. How are the long-term economic benefits of vaccination geographically distributed? Do urban areas benefit more than rural areas?

Facilitated by a research grant from GSK Biologicals, RAND Europe took part in a study which enhanced CGE models for a sub-Saharan country to include the impact of health benefits, in particular malaria control. Simulations of the model focused on how the economy may respond to malaria vaccination of children under the age of 5. The overall aim of the study was to enhance our understanding of the role that health investments can play in stimulating growth in developing countries and to improve health policies. Given the novelty of this approach, the aspiration was that the research would also support academics and researchers seeking to further improve analysis in this area.

Having more detailed and varied information can help policymakers make the best decisions for their country’s short- and long-term objectives. With regard to diseases like malaria, intervention strategies exist that are within the remit of a political decision-making process, but policymakers may not know the full economic and societal impacts of the disease. This research aims to provide a better understanding of the extent to which investing in the fight against malaria is a sustainable long-term investment.


To develop the model, researchers looked at microeconomic details, such as household behaviour, to provide a foundation for macroeconomic assessments:

  • Researchers took into account decisions from all economic actors, such as households, firms, the government, and foreign entities, so that their economic interactions could lead to a balanced economy through changing prices.
  • The team added an aspect that explicitly concerns malaria’s effect on workers.
  • Researchers examined what happens to economic growth under five different scenarios: ranging from a scenario covering 20 per cent of all children under the age of five to a scenario with malaria vaccination of all children.


  • Malaria vaccination with 100% coverage was projected to increase the GDP of Ghana over 30 years by US$6.93 billion (in 2015 prices) above the baseline without vaccination, equivalent to an increase in annual GDP growth of 0.5%.
  • Projected GDP per capita would increase in the first year due to immediate reductions in time lost from work by adults caring for children with malaria, then decrease for several years as reductions in child mortality increase the number of dependent children, then show a sustained increase after Year 11 due to long-term productivity improvements in adults resulting from fewer malaria episodes in childhood.
  • Investing in improving childhood health by vaccinating against malaria could result in substantial long-term macroeconomic benefits when these children enter the workforce as adults. These macroeconomic benefits are not captured by conventional economic evaluations and constitute an important potential benefit of vaccination.