Paul G. Shekelle

Photo of Paul Shekelle
Director, Southern California Evidence-Based Practice Center, RAND Corporation
Santa Monica Office


Ph.D., UCLA School of Public Health; M.D., Duke University; M.P.H., University of California, Los Angeles; B.S. in chemistry / biology, University of Illinois at Urbana-Champaign

Media Resources

This researcher is available for interviews.

To arrange an interview, contact the RAND Office of Media Relations at (310) 451-6913, or email

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Paul G. Shekelle is a staff physician at the West Los Angeles Veterans Affairs Medical Center and has served as director of the Southern California Evidence-based Practice Center for the RAND Corporation since 1997. He is also a professor of medicine at the University of California, Los Angeles (UCLA) School of Medicine. He is widely recognized in the field of guidelines, quality measurement, and evidence-based medicine. Dr. Shekelle has extensive experience in the health care arena and was previously the methodologist for the Agency for Health Care Policy and Research (now the Agency for Healthcare Research and Quality AHRQ) Low-Back Guidelines Panel, and he has participated in a number of other guideline development activities. He is the immediate past-chair of the Clinical Guidelines Committee of the American College of Physicians.

After receiving a B.S. in both biology and chemistry at the University of Illinois, Dr. Shekelle earned his M.D. in 1982 from Duke University. He completed his internship, residency, and fellowship at UCLA, where he also obtained his M.P.H. in 1989 and his Ph.D. in 1993.

Concurrent Non-RAND Positions

Chief of General Internal Medicine, Veterans Affairs West Los Angeles

Recent Projects

  • Comparative Effectiveness of Bariatric Surgery and Nonsurgical Therapy in Adults With Metabolic Conditions and a Body Mass Index of 30.0 to 34.9 kg/m²
  • Surveillance and Identification of Triggers in Updating Systematic Reviews for the EHC Program
  • Updating & Expanding Systematic Reviews of Health Information Technology Literature
  • Critical Analysis of the Evidence for Patient Safety Practices

Selected Publications

Maggard-Gibbons M, Maglione M, Livhits M, Ewing B, Maher AR, Hu J, Li Z, Shekelle PG, "Bariatric surgery for weight loss and glycemic control in nonmorbidly obese adults with diabetes: a systematic review," JAMA, 309(21):2250-2261, 2013

Wachter RM, Pronovost P, Shekelle P., "Strategies to improve patient safety: the evidence base matures," Ann Intern Med, 158(5 Pt 1):350-352, 2013

Hempel, S., Newberry, S., Maher, A., Wang, Z., Miles, J., Shanman, R., Johnsen, B. & Shekelle, P., "Probiotics for the prevention and treatment of antibiotic-associated diarrhea: A systematic review and meta-analysis," JAMA, 307(18):1959-1969, 2012

Ruelaz Maher, A, Maglione, M, Bagley, S, Suttorp, M, Hu, J, Ewing, B, Wang, Z, Timmer, M, Sultzer, D, Shekelle, PG,, "Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis.," JAMA, 306(12):1359-1369, 2011

Schneider-Chafen, J., S, Newbery, M. Riedl, D. Bravata, M. Maglione, M. Suttorp, V. Sundaram, N. Paige, A. Towfigh, B. Hulley, P.G Shekelle, "Diagnosing and Managing Common Food Allergies: A Systematic Review.," JAMA, 303(18):1848-1856, 2010

Coker TR, Chan LS, Newberry SJ, Limbos MA, Suttorp MJ, Shekelle PG, Takata GS., "Diagnosis, microbial epidemiology, and antibiotic treatment of acute otitis media in children: a systematic review," JAMA, 304(19):2161-2169, 2010

Honors & Awards

  • 2011 Under Secretary's Award in Health Services Research, Veterans Affairs

Recent Media Appearances

Interviews: Los Angeles Times; Reuters Health; Scripps Howard News Service; Time Magazine; USA Today; Wall Street Journal

Commentary: British Medical Journal; Journal of Health Services Research and Policy; Lancet; New England Journal of Medicine