Reducing the Global Burden of Acute Lower Respiratory Infections in Children

The Contribution of New Diagnostics

Published in: Nature, v. 444, Suppl. 1, 23 Nov. 2006, p. 9-18

by Yee-Wei Lim, Mark Steinhoff, Federico Girosi, Douglas Holtzman, Harry Campbell, Rob Boer, Robert Black, Kim Mulholland

Read More

Access further information on this document at Nature

This article was published outside of RAND. The full text of the article can be found at the link above.

Acute lower respiratory infections (ALRIs) are the primary killer of children in developing countries. Many children with ALRIs are not properly diagnosed, and overuse of antibiotics has led to increasing drug resistance. The introduction of simple and widely accessible diagnostic tests could significantly reduce deaths among children with ALRIs and reduce the inappropriate use of antibiotics.

This report is part of the RAND Corporation External publication series. Many RAND studies are published in peer-reviewed scholarly journals, as chapters in commercial books, or as documents published by other organizations.

Our mission to help improve policy and decisionmaking through research and analysis is enabled through our core values of quality and objectivity and our unwavering commitment to the highest level of integrity and ethical behavior. To help ensure our research and analysis are rigorous, objective, and nonpartisan, we subject our research publications to a robust and exacting quality-assurance process; avoid both the appearance and reality of financial and other conflicts of interest through staff training, project screening, and a policy of mandatory disclosure; and pursue transparency in our research engagements through our commitment to the open publication of our research findings and recommendations, disclosure of the source of funding of published research, and policies to ensure intellectual independence. For more information, visit

The RAND Corporation is a nonprofit institution that helps improve policy and decisionmaking through research and analysis. RAND's publications do not necessarily reflect the opinions of its research clients and sponsors.