Longitudinal Quality of Life in Low-Income Men in a State-Funded Prostate Cancer Treatment Program

Published In: Journal of Health Care For the Poor and Underserved, v. 19, no. 1, Feb. 2008, p. 200-215

by Mary Wassel Zavala, Sally L. Maliski, Lorna Kwan, David C. Miller, Arlene Fink, Mark Litwin

Read More

Access further information on this document at muse.jhu.edu

This article was published outside of RAND. The full text of the article can be found at the link above.

OBJECTIVES: To evaluate longitudinal changes in disease-specific health-related quality of life (HRQOL) among a cohort of low-income men treated for prostate cancer. METHODS: Three hundred fifty-seven participants in a state-funded program that provides free prostate cancer treatment to uninsured, low-income men completed written surveys and telephone interviews containing validated measures of general and disease-specific HRQOL. Assessments were made at study enrollment and at subsequent times. Determinants of change were identified with repeated-measures analyses. RESULTS: The authors found a significant interaction between the acute surgical treatment effects and time of assessment. Men exposed longer to the program's supportive and educational interventions reported less severe declines in post-operative urinary and bowel HRQOL than others. CONCLUSIONS: Demographic covariates predicted general and disease-specific domains of HRQOL. Among patients treated with surgery, longer duration of pre-treatment program enrollment was associated with better outcomes.

This report is part of the RAND Corporation External publication series. Many RAND studies are published in peer-reviewed scholarly journals, as chapters in commercial books, or as documents published by other organizations.

Our mission to help improve policy and decisionmaking through research and analysis is enabled through our core values of quality and objectivity and our unwavering commitment to the highest level of integrity and ethical behavior. To help ensure our research and analysis are rigorous, objective, and nonpartisan, we subject our research publications to a robust and exacting quality-assurance process; avoid both the appearance and reality of financial and other conflicts of interest through staff training, project screening, and a policy of mandatory disclosure; and pursue transparency in our research engagements through our commitment to the open publication of our research findings and recommendations, disclosure of the source of funding of published research, and policies to ensure intellectual independence. For more information, visit www.rand.org/about/research-integrity.

The RAND Corporation is a nonprofit institution that helps improve policy and decisionmaking through research and analysis. RAND's publications do not necessarily reflect the opinions of its research clients and sponsors.