Erectile Aid Use By Men Treated for Localized Prostate Cancer

Published In: The Journal of Urology, v. 182, no. 2, Aug. 2009, p. 649-654

Posted on RAND.org on January 01, 2009

by Jonathan Bergman, John L. Gore, David F. Penson, Lorna Kwan, Mark Litwin

Read More

Access further information on this document at Elsevier, Inc.

This article was published outside of RAND. The full text of the article can be found at the link above.

PURPOSE: The authors evaluated associations between demographic and clinical characteristics, quality of life outcome measures and erectile aids in men treated for localized prostate cancer. MATERIALS AND METHODS: Patients had clinically localized prostate cancer, were not using erectile aids at baseline and chose treatment with radical prostatectomy (275), external beam radiotherapy (70) or brachytherapy (80). Patient characteristics and health related quality of life outcomes were prospectively assessed at baseline and at regular intervals up to 48 months after treatment. Outcomes were assessed with SF-36i, the American Urological Association symptom index and UCLA-PCI. The authors categorized use of a phosphodiesterase type 5 inhibitor, urethral alprostadil suppositories, penile injection therapy or a vacuum erection device after treatment as erectile aid use. They created a multivariate model examining baseline demographic, clinical and health related quality of life covariates associated with erectile aid use. RESULTS: Of the 425 patients 237 (56%) used an erectile aid at some point during the posttreatment period. In our multivariate model patients treated with external beam radiation were less likely to use an aid (OR 0.34, 95% CI 0.16-0.69) and men with significant sexual bother (OR 2.68, 95% CI 1.37-5.23), or with 1 or more comorbidities (OR 1.80, 95% CI 1.08-2.93) were more likely to use an aid. Patient demographic characteristics were not associated with erectile aids. CONCLUSIONS: After treatment for localized prostate cancer more than half of men use erectile aids, especially when they are significantly bothered by dysfunction. This is most pronounced after radical prostatectomy and in men with significant comorbidity.

This report is part of the RAND Corporation external publication series. Many RAND studies are published in peer-reviewed scholarly journals, as chapters in commercial books, or as documents published by other organizations.

The RAND Corporation is a nonprofit institution that helps improve policy and decisionmaking through research and analysis. RAND's publications do not necessarily reflect the opinions of its research clients and sponsors.