Toward an Asthma Patient-Reported Outcome Measure for Use in Digital Remote Monitoring

Published in: Journal of Asthma (2021). doi: 10.1080/02770903.2021.1955378

Posted on on September 22, 2021

by Robert S. Rudin, Nabeel Qureshi, Dinah Foer, Anuj K. Dalal, Maria Orlando Edelen

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To develop and test a patient-reported outcome measure (PROM) for suitability in digital remote asthma symptom monitoring to identify uncontrolled asthma.


We modified a 5-item PROM that does not require a license, the asthma control measure (ACM), from a one-month to one-week lookback period, and evaluated it using the 5-item asthma control questionnaire (ACQ-5). We recruited subjects with asthma through MTurk, an online platform.


In a sample of 498 subjects, the ACM identified uncontrolled asthma with sensitivity 0.99 and specificity 0.65. The two measures correlated with r = 0.81.


The ACM modified to a weekly lookback period can differentiate patients with well-controlled asthma from those with uncontrolled asthma. This PROM does not require a license and can be used in digital remote monitoring interventions.

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