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Hepatitis C

Journal Article

Assessing and Expanding the Evidence Base for Project ECHO and ECHO-Like Models: Findings of a Technical Expert Panel

Building a strong evidence base will help leverage the innovative aspects of EELM by better understanding how, why, and in what contexts EELM improve care access, quality, and delivery, while also improving provider satisfaction and capacity.

Jun 3, 2020
Report

Subscription Models for Prescription Drugs: The Motivation, Potential, and Limitations of a New Payment Model

The authors argue that, conceptually, the main advantage of subscription models over traditional prescription drug payment arrangements is that they could reduce some sources of uncertainty in spending for payers and in revenue for manufacturers.

May 21, 2020
Report

Identifying Safety-Net Resources at Health Centers to Prevent Infectious Disease Transmission Resulting from the Opioid Epidemic

This study highlights factors that affect Community Health Centers' ability to reduce infectious disease transmission related to the opioid epidemic.

Jun 18, 2019
Journal Article

A Transitioning Epidemic: How The Opioid Crisis Is Driving The Rise In Hepatitis C

The 2010 reformulation of Oxycontin to prevent abuse of the drug (by making it crush-proof and therefore impossible to dissolve in liquid) had the unintended effect of driving some users to switch to heroin, which contributed to a dramatic rise in Hepatitis C.

Mar 13, 2019
Commentary

Opioids and a Crisis of Unintended Consequences

The pain medicine OxyContin was reformulated in 2010 to make it more difficult to crush or dissolve. But this had unintended consequences, including a rise in hepatitis C infections as drug abusers switched from taking OxyContin to injecting heroin.

Feb 20, 2019
Blog

State of the Union, OxyContin, Appalachia: RAND Weekly Recap

This weekly recap focuses on insights from RAND after the State of the Union, public-health impacts of reformulating OxyContin, STEM jobs in Appalachia, and more.

Feb 8, 2019
News Release

Reformulation of OxyContin to Discourage Abuse Linked to Higher Rates of Hepatitis C Infections

To discourage drug abuse, the pain medicine OxyContin was reformulated in 2010, making it difficult to crush or dissolve. This led to a large rise in hepatitis C infections as drug abusers switched from OxyContin to injectable heroin.

Feb 4, 2019
Journal Article

The Association Between Implementation Strategy Use and the Uptake of Hepatitis C Treatment in a National Sample

Veterans Health Administration sites that used more ERIC-recommended implementation strategies delivered more evidence-based Hepatitis C treatments.

Jun 6, 2017
Report

Hepatitis C: Understanding factors that influence the physicians' treatment decisions

A study investigating the decisionmaking process undertaken by physicians when prescribing treatment for Hepatitis C and the comparative influence and importance of specific factors and combinations of factors.

Aug 19, 2016
Commentary

Paying for Pricey Medications: Debt Financing Options Could Provide a Solution

A new approach may be needed to finance an emerging breed of expensive but highly effective pharmaceuticals and vaccines. The health care industry could learn from other industry approaches such as equipment leases or supplier-financed credit.

Jun 22, 2015
Report

Alternative Financing Schemes May Be Needed to Pay for Expensive New Medications

In an era of $1,000-a-pill medications, a new approach may be needed to finance an emerging breed of highly expensive pharmaceuticals and vaccines. Health care could learn from other industries, where it is common for suppliers to encourage investment through approaches such as equipment leases or supplier-financed credit.

Mar 11, 2015
News Release

Alternative Financing Schemes May Be Needed to Pay for Expensive New Medications

In an era of $1,000-a-pill medications, a new approach may be needed to finance an emerging breed of highly expensive pharmaceuticals and vaccines. Health care could learn from other industries, where it is common for suppliers to encourage investment through approaches such as equipment leases or supplier-financed credit.

Mar 11, 2015
Report

Hepatitis C: A projection of the healthcare and economic burden in the UK

Work presented in this report sought to assess the healthcare and economic burden of the hepatitis C virus (HCV) infection in the United Kingdom using a cohort simulation model.

Jan 11, 2013
Journal Article

Substance Use and Other Risk Factors for Unprotected Sex: Results from an Event-Based Study of Homeless Youth

This study of condom use among homeless youth in Los Angeles County found that a broad range of individual, relationship, and contextual factors play a role in condom use.

Aug 1, 2012
Journal Article

Social, Structural and Behavioral Drivers of Concurrent Partnerships Among African American Men in Philadelphia

African American men view sexual relationships with non-main partners as riskier; concurrent relationships are acceptable and often expected.

Oct 1, 2011
Journal Article

Patient and Provider Characteristics Associated with the Decision of HIV Coinfected Patients to Start Hepatitis C Treatment

A patient's decision to start or defer hepatitis C treatment is influenced by the stage of their disease and by their providers' confidence about the efficacy of hepatitis C treatment.

Sep 1, 2011
Journal Article

Patient Characteristics Associated with HCV Treatment Adherence, Treatment Completion and Sustained Virologic Response in HIV Co-Infected Patients

Good mental health may be an indicator of readiness to adhere to treatment for Hepatitis C among individuals who also have HIV.

Jan 1, 2011
Journal Article

Pharmacy Participation in Non-Prescription Syringe Sales in Los Angeles and San Francisco Counties, 2007

California pharmacies are more likely to participate in a voluntary program allowing limited sale of syringes to adults without a prescription if they think syringe access is important for preventing HIV among drug users.

Jan 1, 2010
Journal Article

Three Years After Legalization of Nonprescription Pharmacy Syringe Sales in California: Where Are We Now?

Many California local health jurisdictions with significant numbers of HIV cases have approved disease prevention demonstration projects, which permit limited sale of syringes to adults without a prescription

Jan 1, 2010
Journal Article

Treat Early or Wait and Monitor? A Qualitative Analysis of Provider Hepatitis C Virus Treatment Decision-Making in the Context of HIV Coinfection

Liver disease is a leading cause of death among patients with HIV coinfected with hepatitis C (HCV); yet, studies show that less than 10% receive HCV treatment, in part because of limited treatment response, high treatment toxicity, and psychosocial barri

Jan 1, 2009

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