The goal of the topic brief is to identify key management strategies for infantile epilepsy; provide an overview of clinical practice guidelines, systematic reviews, and randomized controlled trials that assess infantile epilepsy; and highlight evidence gaps.
Aducanumab, a weight-dosed Alzheimer's drug, is available in two fixed-dose vial sizes. This may result in large amounts of discarded drug and wasteful spending. More-efficient vial sizes could save Medicare money if the drug is approved for widespread use.
In a predominantly African-American sample of older adults, worsening of sleep efficiency was associated with poorer cognitive function. Improving sleep health may support Alzheimer's prevention and reduce health disparities.
More fragmented sleep and longer periods of wakefulness after bedtime among a group of low-income African American adults were associated with lower cognitive function such as poor attention and visuospatial ability. Improving sleep may support prevention of Alzheimer's and related dementias.
The RAND Corporation and the University of Pittsburgh will study residents of two predominantly Black neighborhoods in Pittsburgh to examine how exposure to the legacies of structural racism at the neighborhood and individual levels may contribute to the risk of Alzheimer's disease and related dementia in African Americans.
The cover story describes a yearlong study of a group of military veterans experiencing homelessness in Los Angeles. Other features examine the global digital skills gap and the magnitude and sources of disagreement among gun policy experts.
The potential gains from women-focused research are substantial, given the limitations in knowledge about disease development and impacts for women relative to men. Savings would include increased life years, fewer disruptions to work productivity, and fewer years with disease and functional dependence.
The trend within health care services toward remote care and self-management for people with multiple sclerosis has not included adequate support to carers. Greater investment to support the needs of carers could support the informal care they provide, as well as the carer as an individual.
An examination of the impact of increased funding for research on Alzheimer's disease and Alzheimer's disease-related dementias in women showed that small investments in women's health research can yield large gains, including benefits above investing in general research.
An analysis of migraine diagnostic symptoms among women experiencing migraine from the WGHS recruitment sample to assess whether there were clusters of specific symptoms that might also have a genetic basis.