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Neurological Disorders

Journal Article

Estimated Wasteful Spending on Aducanumab Dispensing in the U.S. Medicare Population: A Cross-Sectional Analysis

Aducanumab, a weight-dosed Alzheimer's drug, is available in two fixed-dose vial sizes. This may result in large amounts of discarded drug and wasteful spending. More-efficient vial sizes could save Medicare money if the drug is approved for widespread use.

Aug 11, 2022
Blog

Synthetic Opioids, Ukrainian Grain, the Metaverse: RAND Weekly Recap

This weekly recap focuses on countering the illegal flow of synthetic opioids, freeing up Ukrainian grain to prevent famine, the importance of defining the metaverse, and more.

Jun 24, 2022
Journal Article

Sleep Disturbances, Changes in Sleep, and Cognitive Function in Low-Income African Americans

In a predominantly African-American sample of older adults, worsening of sleep efficiency was associated with poorer cognitive function. Improving sleep health may support Alzheimer's prevention and reduce health disparities.

Jun 23, 2022
News Release

Poor Sleep and Nighttime Wakefulness Associated with Diminished Cognitive Function Among African Americans

More fragmented sleep and longer periods of wakefulness after bedtime among a group of low-income African American adults were associated with lower cognitive function such as poor attention and visuospatial ability. Improving sleep may support prevention of Alzheimer's and related dementias.

Jun 15, 2022
News Release

Research Project Will Probe Role of Structural Racism in Development of Dementias and Cognitive Decline Among African Americans

The RAND Corporation and the University of Pittsburgh will study residents of two predominantly Black neighborhoods in Pittsburgh to examine how exposure to the legacies of structural racism at the neighborhood and individual levels may contribute to the risk of Alzheimer's disease and related dementia in African Americans.

Mar 14, 2022
Periodical

RAND Review: March-April 2022

The cover story describes a yearlong study of a group of military veterans experiencing homelessness in Los Angeles. Other features examine the global digital skills gap and the magnitude and sources of disagreement among gun policy experts.

Mar 10, 2022
Report

Investment in Women's Health Research Could Reap Large Societal Benefits

The potential gains from women-focused research are substantial, given the limitations in knowledge about disease development and impacts for women relative to men. Savings would include increased life years, fewer disruptions to work productivity, and fewer years with disease and functional dependence.

Oct 11, 2021
News Release

Nearly a Third of Americans Use Gray Market When Hiring Caregivers for the Elderly and Those with Dementia

Nearly a third of Americans who arranged for paid care for an older person or someone with dementia employed workers who were not hired through a regulated agency.

Jun 21, 2021
Commentary

The Informal Carers Who Help People with MS Need Support More Than Ever

The trend within health care services toward remote care and self-management for people with multiple sclerosis has not included adequate support to carers. Greater investment to support the needs of carers could support the informal care they provide, as well as the carer as an individual.

May 28, 2021
Report

The Impact of Funding Brain Health Research Focused on Women

An examination of the impact of increased funding for research on Alzheimer's disease and Alzheimer's disease-related dementias in women showed that small investments in women's health research can yield large gains, including benefits above investing in general research.

Apr 22, 2021
Journal Article

Sleep Health: An Opportunity for Public Health to Address Health Equity

In this review, we describe current conceptualizations of sleep health and highlight findings linking sleep with cardiovascular disease, obesity, mental health, and neurodegenerative disease.

Mar 16, 2021
Journal Article

Association of Genetic Variants With Migraine Subclassified by Clinical Symptoms in Adult Females

An analysis of migraine diagnostic symptoms among women experiencing migraine from the WGHS recruitment sample to assess whether there were clusters of specific symptoms that might also have a genetic basis.

Feb 19, 2021
Journal Article

The Foreclosure Crisis, Community Change, and the Cognitive Health of Older Adults

Community-level foreclosures are associated with a faster decline in individual cognition at older ages, with implications for the cognitive health of older adults.

Dec 1, 2020
Journal Article

Meta-issues: On Writing Scientific Manuscripts With a Stakeholder Group of Persons Living With Dementia

Writing scientific papers with stakeholders who had dementia posed special challenges.

Jun 5, 2020
Journal Article

Contributions of Persons Living With Dementia to Scientific Research Meetings: Results From the National Research Summit on Care, Services, and Supports for Persons With Dementia and Their Caregivers

A stakeholder group of persons living with dementia influenced the agenda and outcomes of a national research summit on care, services, and supports for persons living with the disease.

Apr 1, 2020
Journal Article

The Experiences of Persons Living with Dementia Planning for a Dementia Research Meeting: Lessons Learned From the National Research Summit on Care, Services, and Supports for Persons With Dementia and Their Caregivers

A stakeholder group of individuals living with dementia made valuable contributions to a research summit on the disease.

Apr 1, 2020
Report

Neurological Effects of Repeated Exposure to Military Occupational Levels of Blast: A Review of Scientific Literature

There is increasing concern over the common, repetitive forms of blast to which military members are exposed during service, and how those exposures could affect the central nervous system. The authors of this report review the relevant literature.

Mar 18, 2020
Journal Article

Effect of Early-Stage Alzheimer's Disease on Household Financial Outcomes

Our goal in this study is estimate, on net, the financial effects of early-stage Alzheimer's Disease, from the start of first symptoms to diagnosis, on individuals and their families.

Mar 10, 2020
Brochure

Effecting Change, Improving Health

The RAND Corporation is dedicated to transforming the wellbeing of all people by improving health care systems in the United States and abroad.

Feb 7, 2020
Report

Exploring the societal burden of multiple sclerosis: A study into the non-clinical impact of the disease, including changes with progression

We looked at the non-clinical impacts of multiple sclerosis (MS) on the individual with MS, their carers and wider society, focusing on disease progression. We used a rapid evidence assessment and key informant interviews.

Nov 18, 2019

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RAND Topic:
Neurological Disorders

Research conducted by

RAND Health Care