Statins and Dementia

Published in: Archives of Neurology, v. 58, no. 7, Editorial, July 2001, p. 1169-1170

Posted on RAND.org on December 31, 2000

by Beatrice A. Golomb, Beth Jaworski

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Use of statin cholesterol-lowering drugs is observationally associated with lower rates of Alzheimer disease (AD). The authors make an even stronger point: data are consistent with and indeed can be taken to support the contrary conclusion--that high cholesterol protects against dementia. Lipid-lowering drugs are used in the context of--and may serve statistically as a marker for--elevated cholesterol.

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