Approaches and Recommendations for Estimating Minimally Important Differences for Health-Related Quality of Life Measures

Published in: Journal of Chronic Obstructive Pulmonary Disease, v.2, no. 1, Mar. 2005, p. 63-67

Posted on RAND.org on December 31, 2004

by Ron D. Hays, Sepideh S. Farivar, Honghu H. Liu

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The authors describe currently available approaches for estimating the minimally important difference (MID) and their associated strengths and weaknesses. Specifically, we show that anchor-based methods should be the primary method of estimating the MID because of the limitations of distribution-based methods. In addition, we provide recommendations for estimating the MID in future research.

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