Approaches and Recommendations for Estimating Minimally Important Differences for Health-Related Quality of Life Measures

Published in: Journal of Chronic Obstructive Pulmonary Disease, v.2, no. 1, Mar. 2005, p. 63-67

Posted on on January 01, 2005

by Ron D. Hays, Sepideh S. Farivar, Honghu H. Liu

The authors describe currently available approaches for estimating the minimally important difference (MID) and their associated strengths and weaknesses. Specifically, we show that anchor-based methods should be the primary method of estimating the MID because of the limitations of distribution-based methods. In addition, we provide recommendations for estimating the MID in future research.

This report is part of the RAND Corporation External publication series. Many RAND studies are published in peer-reviewed scholarly journals, as chapters in commercial books, or as documents published by other organizations.

The RAND Corporation is a nonprofit institution that helps improve policy and decisionmaking through research and analysis. RAND's publications do not necessarily reflect the opinions of its research clients and sponsors.