Stability and Turbulence in Illegal Drug Markets
ResearchPosted on rand.org Aug 14, 2026Published in: Proceedings of the National Academy of Sciences, Volume 123, No. 33, e2512078123 (2026). DOI: 10.1073/pnas.2512078123
ResearchPosted on rand.org Aug 14, 2026Published in: Proceedings of the National Academy of Sciences, Volume 123, No. 33, e2512078123 (2026). DOI: 10.1073/pnas.2512078123
This article provides a primer on illegal drug markets, with a focus on the structure and nature of these markets and the enterprises involved. The markets for illegal drugs are large, with annual retail expenditures likely exceeding $100 billion in the United States alone. Many drugs are easy to produce, and their high value-to-weight ratios make them attractive to smugglers. Some features of illegal drug markets have been quite stable, such as the small size of retail purchases, in part because most sales are to people who use frequently and typically do not buy in bulk. Between production and consumption, most of these substances cross multiple borders—and often continents—and the mark-ups along the supply chain continue to be substantial. But there have been major changes over the past 15 years. While illegally manufactured synthetic drugs are not new, the proliferation of fentanyl and other synthetic opioids created an overdose crisis in North America and has other countries on high alert. The internet has also made producing and accessing a wide range of drugs and their precursor chemicals easier. The emergence of cryptocurrencies has created new opportunities to hide transactions and launder the proceeds. In addition to highlighting the stability and turbulence in these markets, this article offers ideas for future research and emphasizes the need for monitoring purity-adjusted drug prices, which is critical for understanding supply changes and evaluating interventions in these markets.
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