This report summarizes the results of a study that was performed for the Dutch Ministry of Education, Culture and Science and the Ministry of Agriculture. The study evaluates current capacities to conduct scientific research, in terms of libraries, databases and laboratories, and assesses the future investment needs for scientific research. Investigations were limited to large and very large investments required for the organizations falling under either of the ministries. The methodology of the study consisted of a literature research, interviews, a survey and input from an expert panel to make an inventory of the future investment needs. Results will inform the ministries of future investment needs for the middle and long term and inform policymaking.