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The National Bioethics Advisory Commission (NBAC) was established by executive order in 1995 to advise the National Science and Technology Council and other government entities on bioethical issues arising from research on human biology and human behavior. During the commission’s five-year tenure, it submitted six major reports to the White House that contained 120 recommendations on several complex bioethical issues, including the cloning of human beings, research involving persons with mental disorders that may affect decisionmaking capacity, research with human biological materials, embryonic stem cell research, U.S.-sponsored clinical trials in developing countries, and protection of human research participants. This RAND study was conducted to assess NBAC’s contribution to the policymaking process as it relates to these issues. The author provides a detailed account of the responses to each of NBAC’s six reports from the president, Congress, government, societies and foundations, other countries, and international organizations. Although no legislation has been passed based on NBAC’s recommendations, agencies responsible for a major portion of federally funded research involving human participants-particularly the National Institutes of Health-have adopted several of NBAC’s recommendations and issued research guidelines based on those recommendations.
Table of Contents
Chapter One
Introduction
Chapter Two
NBAC in the Public Eye
Chapter Three
Response to the Cloning Human Beings Report
Chapter Four
Response to the Research Involving Persons with Mental Disorders That May Affect Decisionmaking Capacity Report
Chapter Five
Response to the Research Involving Human Biological Materials: Ethical Issues and Policy Guidance Report
Chapter Six
Response to the Ethical Issues in Human Stem Cell Research Report
Chapter Seven
Response to the Ethical and Policy Issues in International Research: Clinical Trials in Developing Countries Report
Chapter Eight
Response to the Ethical and Policy Issues in Research Involving Human Participants Report
Chapter Nine
Summary
Appendix
Data Collection Methods
The research described in this report was conducted by RAND's Science and Technology Policy Institute for the National Bioethics Advisory Commission.
This report is part of the RAND Corporation Monograph report series. The monograph/report was a product of the RAND Corporation from 1993 to 2003. RAND monograph/reports presented major research findings that addressed the challenges facing the public and private sectors. They included executive summaries, technical documentation, and synthesis pieces.
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