Purchase Print Copy

 FormatList Price Price
Add to Cart Paperback22 pages $15.00 $12.00 20% Web Discount

A continuation of P-1550, Some Mathematical Aspects of Chemotherapy-I: One-organ Models, which considers a model of the distribution of a compound within the plasma flowing through a capillary bed and within the extracellular space and intracellular space. The model includes the possibility of the reaction of the drug with a component of the intracellular space. The present paper extends the model to include the effects of the major tissues of the body and circulation. An attempt is made to show the relationship of this general problem to feedback problems, input-output analysis, and transportation problems arising in economic and engineering control processes. An extension of the model discussed in P-1550, to include the effects of the major tissues of the body and circulation. An attempt is made to show the relationship of this general problem to feedback problems, input-output analysis, and transportation problems arising in economic and engineering control processes. 22 pp.

This report is part of the RAND Corporation paper series. The paper was a product of the RAND Corporation from 1948 to 2003 that captured speeches, memorials, and derivative research, usually prepared on authors' own time and meant to be the scholarly or scientific contribution of individual authors to their professional fields. Papers were less formal than reports and did not require rigorous peer review.

This research in the public interest was supported by RAND, using discretionary funds made possible by the generosity of RAND's donors, the fees earned on client-funded research, and independent research and development (IR&D) funds provided by the Department of Defense.

The RAND Corporation is a nonprofit institution that helps improve policy and decisionmaking through research and analysis. RAND's publications do not necessarily reflect the opinions of its research clients and sponsors.