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A description of short-term effects of LSD. The hypothesis tested was that LSD would produce a rapid lowering of defenses resulting in (1) lower anxiety, (2) attitudinal changes, particularly in the form of decreased dogmatism and projection of aggression, and (3) increases in certain performance tests of fluency, flexibility, and originality. The samples consisted of 15 experimental and 14 comparison subjects, most of whom were professional research personnel. The hypothesis was generally confirmed for the anxiety and attitude tests, but not for the performance tests. (See also P-2575.)

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