Input-Output Relations for Axo-Somatic Activation in a Neuron Model.

Ronald J. MacGregor

Expert InsightsPublished 1967

Experimental findings have suggested that axodendritic activation is the primary source of nonlinear integration among input pulses, while axosomatic activation mediates a relatively inflexible driving action on the cell. A theoretical basis for this distinction was previously examined and a model was presented to account for the nonlinear properties of axodendritic activation. The present study addresses the properties of axosomatic activation with a digital computer simulation of the elicitation of spikes by postsynaptic potentials. Input-output relations for regular and irregular temporal patterns of excitatory activation, and for combined excitatory and inhibitory activation, are presented. The results corroborate the hypothesis. (See also RM-4877.) 28 pp. Ref.

Document Details

  • Copyright: RAND Corporation
  • Availability: Web Only
  • Year: 1967
  • Pages: 28
  • Document Number: P-3672

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MacGregor, Ronald J., Input-Output Relations for Axo-Somatic Activation in a Neuron Model. Santa Monica, CA: RAND Corporation, 1967. https://www.rand.org/pubs/papers/P3672.html.
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