The validity of the brief (eight-item) acculturation measure fielded as part of the Hispanic Health and Nutrition Examination Survey (H-HANES) was examined using data from an independent household sample of Mexican Americans in Los Angeles. Although a factor analysis identified two dimensions — language use and ethnic background — which replicated prior analysis of H-HANES data, a unidimensional scaling of all eight items was also supported by the results. When compared with a more comprehensive (26-item) acculturation measure, the brief H-HANES acculturation measure demonstrated equally high internal reliability, and was an equally strong predictor of two validity indicators — generation and number of years in the United States. Both the brief H-HANES and the comprehensive acculturation measures showed similar relationships to a variety of demographic and health status variables. These findings suggest that, among Mexicans in Los Angeles, brevity of the H-HANES acculturation measure does not reduce the measure's internal reliability or validity relative to other commonly used and more comprehensive acculturation measures.