A mathematical model of drug distribution in the body; implications for cancer chemotherapy [by] Richard Bellman [and others]

by Richard Ernest Bellman, John A. Jacquez, Robert E. Kalaba, Bella Kotkin

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A mathematical model of the processes occurring in the distribution of a drug in the body. The model makes specific predictions concerning the cell permeability and reaction rates between drug and cell-enzyme molecule that are required to obtain marked localization by means of intra-arterial drug injection. 35 pp.

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