A Mathematical Model of Placental Oxygen Transfer.

by T. H. Kirschbaum, Norman Shapiro

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A mathematical model of placental oxygen transfer is used to argue that the experimentally observed control of fetal oxygen concentration in fetal lambs can be explained by the nature of oxyhemoglobin dissociation functions and the differences between these functions in fetal and maternal blood. It is not essential to the explanation to posit any mechanisms responding to a p02 sensor or any changes in fetal, maternal, or placental vascular structures. Equally unnecessary are assumed alterations in the physical or chemical structure of placental membranes. 53 pp. Refs. (Authors)

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