Cover: A Simulation Study of Coincidence Detection in the Dendrites of a Single Nerve Cell

A Simulation Study of Coincidence Detection in the Dendrites of a Single Nerve Cell

Published 1969

by Ronald J. MacGregor

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Results of simulations indicating the ability of a typical nerve cell to discriminate between coincident pulses as compared with two pulses a short time interval apart. The simulations are performed with a model for neuroelectric coding processes in a single cell, which includes a representation of dendritic geometry. For this model:(a) the probability that an output spike will be associated in time with a coupled pair of input pulses originating at dendritic synapses is greater when the time interval between the pulses is 0 than when it is 2 msec; (b) both the actual values of probabilities and their differences are generally larger for smooth than for irregular background activity; and (c) the difference is greater the closer together the two synapses.

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