Accounting for Misclassification in Electronic Health Records-derived Exposures Using Generalized Linear Finite Mixture Models
Exposures derived from EHRs may be misclassified, leading to biased estimates of their association with outcomes of interest: finite mixture models can correct biases with no loss of efficiency.
Dec 7, 2017
We designed and tested the feasibility, effectiveness, and sustainability of CQI approaches in substance use disorder treatment settings
Aug 24, 2017
Patients prefer less invasive approaches such as fecal immunochemical test (FIT) for colorectal cancer screening, but the effectiveness of FIT depends on annual screenings for those with negative test results and colonoscopy if FIT tests are positive.
May 23, 2017
Effect of Time to Diagnostic Testing for Breast, Cervical, and Colorectal Cancer Screening Abnormalities on Screening Efficacy: A Modeling Study
Even relatively small delays in diagnostic testing after an abnormal cancer screening test can reduce screening effectiveness, though the impact varies by cancer type.
Each of the diagnostics for colorectal cancer has a different level of evidence supporting its ability to detect cancer and associated risks of serious adverse effects. More research is needed to clarify the evidence base.
Oct 12, 2016
Follow-up was more prompt for women with abnormal mammograms than for women with abnormal fecal occult blood testing or fecal immunochemical tests.
Oct 10, 2016
Screening for colorectal cancer would benefit from re-evaluation of age-based guidelines as well as improved screening completion among the elderly.
Sep 13, 2016
Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
This study systematically reviewed the evidence on the effectiveness, diagnostic accuracy, and harms of colonoscopy, flexible sigmoidoscopy, computed tomographic colonography, and stool tests for colorectal cancer screening.
Jun 27, 2016
Association Between Primary Care Visits and Colorectal Cancer Screening Outcomes in the Era of Population Health Outreach
Patients who visited their primary care provider one or more times were almost twice as likely to be screened for colorectal cancer and about 30 percent more likely receive a follow-up colonoscopy after a positive screening result.
Jun 24, 2016
Estimation of Benefits, Burden, and Harms of Colorectal Cancer Screening Strategies: Modeling Study for the US Preventive Services Task Force
Comparative modeling of colorectal cancer screening methods for previously unscreened adults found that the use of four strategies over different intervals between the ages of 50 and 75 years yielded a comparable balance of benefit and burden.
Jun 21, 2016
Risk of complications within 30 days of a colonoscopy increases with the use of anesthesia services.
Apr 22, 2016
To reduce colorectal cancer mortality, positive fecal blood tests must be followed by colonoscopy.
Feb 22, 2016
The goal of this study is to evaluate the performance of the Spanish version of the PROMIS smoking item banks as compared to the original banks developed in English.
Feb 12, 2016
Validation of Models Used to Inform Colorectal Cancer Screening Guidelines: Accuracy and Implications
We validated 3 colorectal cancer (CRC) microsimulation models against outcomes from the United Kingdom Flexible Sigmoidoscopy Screening (UKFSS) Trial, a randomized controlled trial that examined the effectiveness of one-time flexible sigmoidoscopy screening to reduce CRC mortality.
Jan 26, 2016
Variation in Screening Abnormality Rates and Follow-Up of Breast, Cervical and Colorectal Cancer Screening Within the PROSPR Consortium
This study characterizes variation in screening abnormality rates and timely initial follow-up for common cancer screening tests.
Jan 5, 2016
This study examines the synergies that exist between decision-analytic models and health care utilization data that are increasingly accessible through research networks that assemble data from the growing number of electronic medical record systems.
Cohort Restriction Based on Prior Enrollment: Examining Potential Biases in Estimating Cancer and Mortality Risk
This paper investigates the potential for selection bias, to assess whether restricting cohort studies based on prior enrollment created a cohort with a different risk of cancer or death than the full enrollee population.
Discussion of "A Risk-Based Measure of Time-Varying Prognostic Discrimination for Survival Models," by C. Jason Liang and Patrick J. Heagerty
This article discusses a proposed risk-based measure of time-varying discrimination for determining the value of predictors in time-to-event models.
Current and Projected Characteristics and Unique Health Care Needs of the Patient Population Served by the Department of Veterans Affairs
Veterans who rely on Department of Veterans Affairs (VA) health care are older and less healthy than other veterans. Analysis of a range of data sources showed how the veteran population and demand for VA health care could change in the next decade.
Dec 31, 2015
Resources and Capabilities of the Department of Veterans Affairs to Provide Timely and Accessible Care to Veterans
The Department of Veterans Affairs health care system, with broad resources and capabilities, provides timely and high-quality care to most, but not all, patients. Meeting veterans' needs over the next five years will require additional capacity.
Dec 31, 2015
Misclassification of Breast Imaging Reporting and Data System (BI-RADS) Mammographic Density and Implications for Breast Density Reporting Legislation
The aim of this study was to assess reproducibility of the four-category Breast Imaging Reporting and Data System [BI-RADS] density measure and examine its relationship with a continuous measure of percent density.
Jul 14, 2015
Colonoscopy before age 50 is increasingly common.
Feb 24, 2015