Barbara Del Castello — Publications

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Bridging the Digital to Physical Divide: Evaluating LLM Agents on Benchtop DNA Acquisition

2026
Building Resilience Against Artificial Intelligence–Enabled Biological Threats: Conference Proceedings from a RAND and Helena Workshop

2026
Can LLM Agents Select and Engage with Biological Tools? An Initial Biosecurity Assessment

2026
Developing a Risk-Scoring Tool for Artificial Intelligence–Enabled Biological Design: A Method to Assess the Risks of Using Artificial Intelligence to Modify Select Viral Capabilities

2026
Infinite Potential—Insights from the European Games: After-Action Report from a Sequence of Day After Artificial General Intelligence Exercises

2026
Infinite Potential—Insights from the Viral Uplift Scenario: After-Action Report from a Sequence of Day After Artificial General Intelligence Exercises

2026
Interpreting Dual-Use Biology Benchmarks for Frontier AI: Measurement, Saturation, and Generational Analysis

2026
A Standardized Framework for Assessing High-Risk Life Sciences Research: Defining Objective Criteria That Can Facilitate Expert and AI Reviews of Dangerous Gain-of-Function Research

2026
Testing Large Language Model Agents on the Use of Biological Tools for Nucleic Acid Synthesis Screening Evasion

2026
Assessing the Impacts of Technology Maturity and Diffusion on Malicious Biological Agent Development Capabilities: Demonstrating a Transparent, Repeatable Assessment Method

2025
Documenting Cloud Labs and Examining How Remotely Operated Automated Laboratories Could Enable Bad Actors

2025
Evaluating Safety and Security in Biological Research: A Proposed Tool to Assess Dual-Use Research of Concern and Pathogens with Enhanced Pandemic Potential

2025
Global Risk Index for AI-enabled Biological Tools: Summary Assessment & Methods Report

2025
Mitigating Risks at the Intersection of Artificial Intelligence and Chemical and Biological Weapons

2025
Toward Comprehensive Benchmarking of the Biological Knowledge of Frontier Large Language Models

2025
On the Responsible Development and Use of Chem-Bio AI Models: Comments on Evaluations, Mitigations, and Emerging Trends

2024

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Barbara Del Castello — Publications

Bridging the Digital to Physical Divide: Evaluating LLM Agents on Benchtop DNA Acquisition

Building Resilience Against Artificial Intelligence–Enabled Biological Threats: Conference Proceedings from a RAND and Helena Workshop

Can LLM Agents Select and Engage with Biological Tools? An Initial Biosecurity Assessment

Developing a Risk-Scoring Tool for Artificial Intelligence–Enabled Biological Design: A Method to Assess the Risks of Using Artificial Intelligence to Modify Select Viral Capabilities

Infinite Potential—Insights from the European Games: After-Action Report from a Sequence of Day After Artificial General Intelligence Exercises

Infinite Potential—Insights from the Viral Uplift Scenario: After-Action Report from a Sequence of Day After Artificial General Intelligence Exercises

Interpreting Dual-Use Biology Benchmarks for Frontier AI: Measurement, Saturation, and Generational Analysis

A Standardized Framework for Assessing High-Risk Life Sciences Research: Defining Objective Criteria That Can Facilitate Expert and AI Reviews of Dangerous Gain-of-Function Research

Testing Large Language Model Agents on the Use of Biological Tools for Nucleic Acid Synthesis Screening Evasion

Assessing the Impacts of Technology Maturity and Diffusion on Malicious Biological Agent Development Capabilities: Demonstrating a Transparent, Repeatable Assessment Method

Documenting Cloud Labs and Examining How Remotely Operated Automated Laboratories Could Enable Bad Actors

Evaluating Safety and Security in Biological Research: A Proposed Tool to Assess Dual-Use Research of Concern and Pathogens with Enhanced Pandemic Potential

Global Risk Index for AI-enabled Biological Tools: Summary Assessment & Methods Report

Mitigating Risks at the Intersection of Artificial Intelligence and Chemical and Biological Weapons

Toward Comprehensive Benchmarking of the Biological Knowledge of Frontier Large Language Models

On the Responsible Development and Use of Chem-Bio AI Models: Comments on Evaluations, Mitigations, and Emerging Trends

Infinite Potential—Insights from the European Games: After-Action Report from a Sequence of Day After Artificial General Intelligence Exercises