Findings illustrate that women with breast cancer are not receiving evidence-based care recommended by their physicians. Although tamoxifen or anastrozole therapy can be recommended for fewer than 5 years when used in conjunction with another agent, these investigators evaluated rates of adherence to prescribed medication, not a change in the physician's prescription. The influence on outcomes of the many possible patterns of lack of compliance with recommended treatment is not known. The extent to which expected outcomes would be hampered by patients using the drug intermittently or by cutting the daily, weekly, or monthly dose is not known.
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