National Heart, Lung, and Blood Institute Working Group on Emergency Department Management of Acute Heart Failure

Research Challenges and Opportunities

Published in: JACC, Journal of the American College of Cardiology, v. 56, no. 5, July 2010, p. 343-351

Posted on on June 30, 2010

by W. Frank Peacock, Eugene Braunwald, William Abraham, Nancy Albert, John Burnett, Rob Christenson, Sean Collins, Deborah Diercks, Gregg C. Fonarow, Judd Hollander, et al.

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This paper details the substance and recommendations arising from a meeting convened by the National Heart, Lung, and Blood Institute in August 2009, to assess the challenges and opportunities of emergency department management of acute heart failure syndrome (AHFS). The assembled faculty represented a large cross section of medical professionals spanning the medical management continuum of patients presenting with acute heart failure and included heart failure cardiologists, emergency physicians, laboratory medicine specialists, nurses, and bench scientists. Their recommendations include proposals regarding the design and conduct of emergency department-based clinical trials, suggestions regarding the development of improved methods for early detection and monitoring of AHFS, and potential needs for expanding translational and applied AHFS focused research and biotechnology. We anticipate that this review will serve as a starting point for future investigations across the spectrum of funding sources.

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