Cover: Pilot Controlled Trial of the Adherence Readiness Program

Pilot Controlled Trial of the Adherence Readiness Program

An Intervention to Assess and Sustain HIV Antiretroviral Adherence Readiness

Published in: AIDS and Behavior, v. 17, no. 9, Nov. 2013, p. 3059-3065

Posted on on January 01, 2013

by Glenn Wagner, Paul Lovely, Stefan Schneider

To pilot the adherence readiness program, 60 patients planning to start HIV antiretrovirals were assigned to usual care (n = 31) or the intervention (n = 29), of whom 54 started antiretrovirals and were followed for up to 24 weeks. At week 24, the intervention had a large effect (50.0 % vs. 16.7 %, d = 0.75) on optimal dose-timing (85+ % doses taken on time) and small effect (54.2 % vs. 43.3 %, d = 0.22) on optimal dose-taking (85+ % doses taken) electronically monitored adherence, and medium effect on undetectable viral load (62 % 0.5 % vs. 43.4 %, d = 0.41), compared to usual care. These intervention benefits on adherence and viral suppression warrant further investigation.

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