Probiotics for Diarrhoea

Published in: Indian Journal of Medical Research, v. 139, Commentary, Mar. 2014, p. 339-341

Posted on RAND.org on March 01, 2014

by Susanne Hempel

Read More

Access further information on this document at www.ncbi.nlm.nih.gov

This article was published outside of RAND. The full text of the article can be found at the link above.

Empirical evidence for the clinical effectiveness of probiotics has shown mixed results and we still know very little about which probiotics work for which indication and group of patients. In order to be of informational value, the effectiveness of probiotics needs to be demonstrated in strong research designs, such as randomized controlled trials, that hold up to scientific scrutiny. The study by Aggarwal and colleagues in this issue shows an application of probiotics that has increasingly become the subject of research interest for the treatment of acute childhood diarrhoea.

This report is part of the RAND Corporation External publication series. Many RAND studies are published in peer-reviewed scholarly journals, as chapters in commercial books, or as documents published by other organizations.

Our mission to help improve policy and decisionmaking through research and analysis is enabled through our core values of quality and objectivity and our unwavering commitment to the highest level of integrity and ethical behavior. To help ensure our research and analysis are rigorous, objective, and nonpartisan, we subject our research publications to a robust and exacting quality-assurance process; avoid both the appearance and reality of financial and other conflicts of interest through staff training, project screening, and a policy of mandatory disclosure; and pursue transparency in our research engagements through our commitment to the open publication of our research findings and recommendations, disclosure of the source of funding of published research, and policies to ensure intellectual independence. For more information, visit www.rand.org/about/principles.

The RAND Corporation is a nonprofit institution that helps improve policy and decisionmaking through research and analysis. RAND's publications do not necessarily reflect the opinions of its research clients and sponsors.