West Virginia leads the USA in opioid overdoses, with a rate more than three times the national average. Post-overdose medications for opioid use disorder (MOUD) are protective against future deaths, yet are infrequently prescribed. Mental health disorders increase opioid overdose risk. Given the substantial burden of psychiatric comorbidities among people who overdose, it is important to understand how both MOUD and treatment for co-occurring mental health conditions change following overdoses.
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