An Evidence Map of Treatments for Infantile Epilepsy
Published in: Epilepsy Research, Volume 178 (December 2021). doi: 10.1016/j.eplepsyres.2021.106781
Posted on RAND.org on October 24, 2022
Epilepsy prevalence is high among infants, but treatment guidelines are not clear. We conducted a scoping review of interventions to manage epilepsy in infants, and identified 37 studies. Most studies reported that interventions were effective (22 studies; 76%), but randomized controlled trials were uncommon (7 studies; 19%) and sample sizes were small (range: 2 to 284 participants; mean: 69.4; 95% confidence interval: 49.5, 89.2). Additional high quality research and systematic reviews on interventions for infantile epilepsy are needed to establish better treatment guidelines for the disease.