Topic Brief

Infantile Epilepsy

Published in: Patient-Centered Outcomes Research Institute website (December 2019)

Posted on RAND.org on October 24, 2022

by Julia Rollison, Arthur Partikian, Goke Akinniranye, Sachi Yagyu, Aneesa Motala, Susanne Hempel

Epilepsy is more common in children than in adults, with several unique childhood-onset epilepsy syndromes. Despite its prevalence, limited research exists on infantile epilepsy. In 2019, PCORI commissioned a topic brief on infantile epilepsy to understand the breadth and quantity of existing evidence on the topic to support funding decisions for future comparative effectiveness research and evidence synthesis.

The goal of the topic brief is to identify key management strategies for infantile epilepsy; provide an overview of clinical practice guidelines, systematic reviews, and randomized controlled trials that assess infantile epilepsy; and highlight evidence gaps.

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