The Structural Genomics Consortium

A knowledge platform for drug discovery

Molly Morgan Jones, Sophie Castle-Clarke, Daniel Brooker, Edward Nason, Farah Huzair, Joanna Chataway

ResearchPublished Mar 10, 2014

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The Structural Genomics Consortium (SGC) supports drug discovery efforts through a unique, open access model of public-private collaboration. This report presents the results of an independent evaluation of the Structural Genomics Consortium, conducted by RAND Europe with the Institute on Governance. The evaluation aimed to establish the role of the SGC within the wider drug discovery and public-private partnership (PPP) landscape, assessing the merits of the SGC open access model relative to alternative models of funding R&D in this space, as well as the key trends and opportunities in the external environment that may impact on the future of the SGC. It also established the incentives and disincentives for investment, strengths and weaknesses of the SGC's model, and the opportunities and threats the SGC will face in the future. This enabled us to assess the most convincing arguments for funding the SGC at present; important trade-offs or limitations that should be addressed in moving towards the next funding phase; and whether funders are anticipating changes either to the SGC or the wider PPP landscape. Finally, we undertook a quantitative analysis to ascertain what judgements can be made about the SGC's past and current performance track record, before unpacking the role of the external environment and particular actors within the SGC in developing scenarios for the future.

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Morgan Jones, Molly, Sophie Castle-Clarke, Daniel Brooker, Edward Nason, Farah Huzair, and Joanna Chataway, The Structural Genomics Consortium: A knowledge platform for drug discovery, RAND Corporation, RR-512-SGC, 2014. As of September 12, 2024: https://www.rand.org/pubs/research_reports/RR512.html
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Morgan Jones, Molly, Sophie Castle-Clarke, Daniel Brooker, Edward Nason, Farah Huzair, and Joanna Chataway, The Structural Genomics Consortium: A knowledge platform for drug discovery. Santa Monica, CA: RAND Corporation, 2014. https://www.rand.org/pubs/research_reports/RR512.html.
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The research described in this report was prepared for and primarily funded by the Structural Genomics Consortium. It was also funded in part by the Policy Research Programme in the Department of Health. The research conducted by RAND Europe.

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