Increasing Antiretroviral Adherence for HIV-positive African Americans (Project Rise)

A Treatment Education Intervention Protocol

Published in: JMIR Research Protocols, v. 5, no. 1, e45, Jan.-Mar. 2016

Posted on RAND.org on April 21, 2016

by Glenn Wagner, Laura M. Bogart, Matt G. Mutchler, Bryce W McDavitt, Kieta D. Mutepfa, Brian Risley

Read More

Access further information on this document at JMIR Research Protocols

This article was published outside of RAND. The full text of the article can be found at the link above.

BACKGROUND: HIV-positive African Americans have been shown to have lower adherence to antiretroviral therapy (ART) than those of other races/ethnicities, yet adherence interventions have rarely been tailored to the needs of this population. OBJECTIVE: We developed and will evaluate a treatment education adherence intervention (called Rise) that was culturally adapted to address the needs of African Americans living with HIV. METHODS: This randomized controlled trial will examine the effects of the Rise intervention on ART adherence and HIV viral load. African Americans on ART who report adherence problems will be recruited from the community and randomly assigned to receive the intervention or usual care for 6 months. The intervention consists of 6-10 individual counseling sessions, with more sessions provided to those who demonstrate lower adherence. Primary outcomes include adherence as monitored continuously with Medication Event Monitoring Systems (MEMS) caps, and viral load data received from the participant's medical provider. Survey assessments will be administered at baseline and month 6. RESULTS: The trial is ongoing. CONCLUSIONS: If effective, the Rise intervention will provide community-based organizations with an intervention tailored to address the needs of African Americans for promoting optimal ART adherence and HIV clinical outcomes.

This report is part of the RAND Corporation external publication series. Many RAND studies are published in peer-reviewed scholarly journals, as chapters in commercial books, or as documents published by other organizations.

The RAND Corporation is a nonprofit institution that helps improve policy and decisionmaking through research and analysis. RAND's publications do not necessarily reflect the opinions of its research clients and sponsors.